ENSDARG00000043820


Danio rerio

Features
Gene ID: ENSDARG00000043820
  
Biological name :nme2a
  
Synonyms : nme2a / NME/NM23 nucleoside diphosphate kinase 2a
  
Possible biological names infered from orthology : Gm20390 / NME1 / NME1-NME2 / NME1-NME2 readthrough / NME2 / NME/NM23 nucleoside diphosphate kinase 1 / NME/NM23 nucleoside diphosphate kinase 2 / Nucleoside diphosphate kinase A / P15531 / P15532 / P22392 / Q01768
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 20788243
Gene end: 20796658
  
Corresponding Affymetrix probe sets: Dr.9836.1.S1_at (Zebrafish Array)   NM_199970_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000064338
Ensembl peptide - ENSDARP00000127219
Ensembl peptide - ENSDARP00000127327
Ensembl peptide - ENSDARP00000154974
NCBI entrez gene - 335716     See in Manteia.
RefSeq - NM_199970
RefSeq - XM_021480031
RefSeq Peptide - NP_956264
swissprot - Q6PC37
ZFIN ID - ZDB-GENE-030131-7656
Ensembl - ENSDARG00000043820
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000031071Gallus gallus
 NME1ENSGALG00000007305Gallus gallus
 NME2ENSGALG00000002932Gallus gallus
 NME1ENSG00000239672Homo sapiens
 NME1-NME2ENSG00000011052Homo sapiens
 NME2ENSG00000243678Homo sapiens
 Gm20390ENSMUSG00000091228Mus musculus
 Nme1ENSMUSG00000037601Mus musculus
 Nme2ENSMUSG00000020857Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nme2b.1 / NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 / NME2* / NME1* / P22392* / P15531* / NME1-NME2* / NME1-NME2 readthrough* / NME/NM23 nucleoside diphosphate kinase 2*...ENSDARG0000010379178
nme2b.2 / NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2 / NME2* / NME1* / P22392* / P15531* / NME1-NME2* / NME1-NME2 readthrough* / NME/NM23 nucleoside diphosphate kinase 2*...ENSDARG0000009942071
nme3 / NME/NM23 nucleoside diphosphate kinase 3 / Q13232* / Q9WV85* / Nucleoside diphosphate kinase 3 *ENSDARG0000010099066
nme4 / NME/NM23 nucleoside diphosphate kinase 4 / O00746* / Q9WV84* / Nucleoside diphosphate kinase, mitochondrial *ENSDARG0000008839054
nme8 / NME/NM23 family member 8 / NME9* / Q86XW9* / NME/NM23 family member 9*ENSDARG0000009894429
nme7 / NME/NM23 family member 7 / Q9Y5B8*ENSDARG0000005619329
nme5 / NME/NM23 family member 5 / P56597* / Q99MH5* / Nucleoside diphosphate kinase homolog 5 *ENSDARG0000004161728
nme6 / Q6DI51 / NME/NM23 nucleoside diphosphate kinase 6 / O75414* / O88425* / Nucleoside diphosphate kinase 6 *ENSDARG0000001613827


Protein motifs (from Interpro)
Interpro ID Name
 IPR001564  Nucleoside diphosphate kinase
 IPR023005  Nucleoside diphosphate kinase, active site
 IPR034907  Nucleoside diphosphate kinase-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006165 nucleoside diphosphate phosphorylation IEA
 biological_processGO:0006183 GTP biosynthetic process IEA
 biological_processGO:0006228 UTP biosynthetic process IEA
 biological_processGO:0006241 CTP biosynthetic process IEA
 biological_processGO:0016310 phosphorylation IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004550 nucleoside diphosphate kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000099420 nme2b.2 / NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2 / NME2* / NME1* / P22392* / P15531* / NME1-NME2* / NME1-NME2 readthrough* / NME/NM23 nucleoside diphosphate kinase 2*...  / complex
 ENSDARG00000043820 nme2a / NME/NM23 nucleoside diphosphate kinase 2a / NME2* / NME1* / Q01768* / P15531* / P15532* / P22392* / Gm20390* / NME1-NME2* / NME1-NME2 readthrough* / Nucleoside diphosphate kinase A ...  / complex
 ENSDARG00000100990 nme3 / NME/NM23 nucleoside diphosphate kinase 3 / Q13232* / Q9WV85* / Nucleoside diphosphate kinase 3 *  / complex
 ENSDARG00000103791 nme2b.1 / NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 / NME2* / NME1* / P22392* / P15531* / NME1-NME2* / NME1-NME2 readthrough* / NME/NM23 nucleoside diphosphate kinase 2*...  / complex






 

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