ENSDARG00000103791


Danio rerio

Features
Gene ID: ENSDARG00000103791
  
Biological name :nme2b.1
  
Synonyms : nme2b.1 / NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
  
Possible biological names infered from orthology : Gm20390 / NME1 / NME1-NME2 / NME1-NME2 readthrough / NME2 / NME/NM23 nucleoside diphosphate kinase 1 / NME/NM23 nucleoside diphosphate kinase 2 / Nucleoside diphosphate kinase A / P15531 / P15532 / P22392 / Q01768
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 48117388
Gene end: 48120285
  
Corresponding Affymetrix probe sets: Dr.1320.1.S1_at (Zebrafish Array)   NM_130926_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000134958
Ensembl peptide - ENSDARP00000136238
NCBI entrez gene - 30083     See in Manteia.
RefSeq - NM_130926
RefSeq Peptide - NP_571001
swissprot - F1RBS6
ZFIN ID - ZDB-GENE-000210-32
Ensembl - ENSDARG00000103791
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000031071Gallus gallus
 NME1ENSGALG00000007305Gallus gallus
 NME2ENSGALG00000002932Gallus gallus
 NME1ENSG00000239672Homo sapiens
 NME1-NME2ENSG00000011052Homo sapiens
 NME2ENSG00000243678Homo sapiens
 Gm20390ENSMUSG00000091228Mus musculus
 Nme1ENSMUSG00000037601Mus musculus
 Nme2ENSMUSG00000020857Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nme2b.2 / NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2 / NME2* / NME1* / P22392* / P15531* / NME1-NME2* / NME1-NME2 readthrough* / NME/NM23 nucleoside diphosphate kinase 2*...ENSDARG0000009942086
nme2a / NME/NM23 nucleoside diphosphate kinase 2a / NME2* / NME1* / Q01768* / P15531* / P15532* / P22392* / Gm20390* / NME1-NME2* / NME1-NME2 readthrough* / Nucleoside diphosphate kinase A ...ENSDARG0000004382078
nme3 / NME/NM23 nucleoside diphosphate kinase 3 / Q13232* / Q9WV85* / Nucleoside diphosphate kinase 3 *ENSDARG0000010099070
nme4 / NME/NM23 nucleoside diphosphate kinase 4 / O00746* / Q9WV84* / Nucleoside diphosphate kinase, mitochondrial *ENSDARG0000008839058
nme8 / NME/NM23 family member 8 / NME9* / Q86XW9* / NME/NM23 family member 9*ENSDARG0000009894431
nme7 / NME/NM23 family member 7 / Q9Y5B8*ENSDARG0000005619329
nme5 / NME/NM23 family member 5 / P56597* / Q99MH5* / Nucleoside diphosphate kinase homolog 5 *ENSDARG0000004161727
nme6 / Q6DI51 / NME/NM23 nucleoside diphosphate kinase 6 / O75414* / O88425* / Nucleoside diphosphate kinase 6 *ENSDARG0000001613825


Protein motifs (from Interpro)
Interpro ID Name
 IPR001564  Nucleoside diphosphate kinase
 IPR023005  Nucleoside diphosphate kinase, active site
 IPR034907  Nucleoside diphosphate kinase-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006165 nucleoside diphosphate phosphorylation IEA
 biological_processGO:0006183 GTP biosynthetic process IMP
 biological_processGO:0006228 UTP biosynthetic process IEA
 biological_processGO:0006241 CTP biosynthetic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0045765 regulation of angiogenesis IMP
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004550 nucleoside diphosphate kinase activity IMP
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000099 brain vasculature brain vasculature malformed , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000114 heart heart composition , abnormal
heart decreased contractility , abnormal
heart decreased functionality , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel malformed , abnormal
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 ZFA:0005020 central artery central artery malformed , abnormal
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 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel malformed , abnormal
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 ZFA:0005034 parachordal vessel parachordal vessel aplastic , abnormal
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 ZFA:0005035 subintestinal vein subintestinal vein absent , abnormal
subintestinal vein malformed , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000100990 nme3 / NME/NM23 nucleoside diphosphate kinase 3 / Q13232* / Q9WV85* / Nucleoside diphosphate kinase 3 *  / complex
 ENSDARG00000099420 nme2b.2 / NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2 / NME2* / NME1* / P22392* / P15531* / NME1-NME2* / NME1-NME2 readthrough* / NME/NM23 nucleoside diphosphate kinase 2*...  / complex
 ENSDARG00000103791 nme2b.1 / NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 / NME2* / NME1* / P22392* / P15531* / NME1-NME2* / NME1-NME2 readthrough* / NME/NM23 nucleoside diphosphate kinase 2*...  / complex
 ENSDARG00000043820 nme2a / NME/NM23 nucleoside diphosphate kinase 2a / NME2* / NME1* / Q01768* / P15531* / P15532* / P22392* / Gm20390* / NME1-NME2* / NME1-NME2 readthrough* / Nucleoside diphosphate kinase A ...  / complex






 

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