ENSDARG00000104222


Danio rerio

Features
Gene ID: ENSDARG00000104222
  
Biological name :inppl1a
  
Synonyms : inositol polyphosphate phosphatase-like 1a / inppl1a
  
Possible biological names infered from orthology : inositol polyphosphate phosphatase like 1 / INPPL1 / O15357 / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 / Q6P549
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 47452630
Gene end: 47479119
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000129999
Ensembl peptide - ENSDARP00000132657
Ensembl peptide - ENSDARP00000138930
swissprot - A0A0J9YJ69
swissprot - A0A0R4IB77
swissprot - A0A0R4ISQ5
ZFIN ID - ZDB-GENE-030131-3904
Ensembl - ENSDARG00000104222
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 INPPL1ENSG00000165458Homo sapiens
 Inppl1ENSMUSG00000032737Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
inppl1b / inositol polyphosphate phosphatase-like 1bENSDARG0000000144241
inpp5d / inositol polyphosphate-5-phosphatase D / Q92835* / Q9ES52* / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 *ENSDARG0000007428334
ocrl / oculocerebrorenal syndrome of Lowe / Q01968* / Q6NVF0* / OCRL, inositol polyphosphate-5-phosphatase* / Inositol polyphosphate 5-phosphatase OCRL-1 *ENSDARG0000007810614
inpp5b / inositol polyphosphate-5-phosphatase B / P32019* / Q8K337* / Type II inositol 1,4,5-trisphosphate 5-phosphatase *ENSDARG0000010368313
synj1 / synaptojanin 1 / O43426*ENSDARG0000002501112
inpp5e / inositol polyphosphate-5-phosphatase E / Q9JII1* / Q9NRR6* / 72 kDa inositol polyphosphate 5-phosphatase *ENSDARG0000010392611
inpp5kb / inositol polyphosphate-5-phosphatase Kb / INPP5K* / Q9BT40* / Q8C5L6* / inositol polyphosphate-5-phosphatase K*ENSDARG0000007861810
inpp5ja / inositol polyphosphate-5-phosphatase Ja / INPP5J* / P59644* / Q15735* / inositol polyphosphate-5-phosphatase J* / Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A *ENSDARG0000007854210
inpp5ka / inositol polyphosphate-5-phosphatase Ka / INPP5K* / Q9BT40* / Q8C5L6* / inositol polyphosphate-5-phosphatase K*ENSDARG0000009956310
inpp5jb / inositol polyphosphate-5-phosphatase Jb / INPP5J* / P59644* / Q15735* / inositol polyphosphate-5-phosphatase J* / Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A *ENSDARG000000933599


Protein motifs (from Interpro)
Interpro ID Name
 IPR000300  Inositol polyphosphate-related phosphatase
 IPR001660  Sterile alpha motif domain
 IPR005135  Endonuclease/exonuclease/phosphatase
 IPR013761  Sterile alpha motif/pointed domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0046856 phosphatidylinositol dephosphorylation IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane
Synthesis of IP3 and IP4 in the cytosol
Interleukin receptor SHC signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000155 somite somite decreased length , abnormal
somite increased width , abnormal
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 ZFA:0000823 rhombomere 5 rhombomere 5 increased width , abnormal
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 ZFA:0000948 rhombomere 3 rhombomere 3 increased width , abnormal
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 ZFA:0001094 whole organism whole organism wholly dorsalized , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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