Manteia

ENSDARG00000074283

Danio rerio

Features

Gene ID:	ENSDARG00000074283

Biological name :	inpp5d

Synonyms :	inositol polyphosphate-5-phosphatase D / inpp5d

Possible biological names infered from orthology :	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 / Q92835 / Q9ES52

Species:	Danio rerio

Chr. number:	6
Strand:	1
Band:
Gene start:	28140816
Gene end:	28192192

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000104271 Ensembl peptide - ENSDARP00000117012 Ensembl peptide - ENSDARP00000153457 swissprot - E7F1C2 swissprot - E9QIN2 ZFIN ID - ZDB-GENE-100922-30 Ensembl - ENSDARG00000074283

See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
inppl1b / inositol polyphosphate phosphatase-like 1b	ENSDARG00000001442	36
inppl1a / inositol polyphosphate phosphatase-like 1a / INPPL1* / O15357* / Q6P549* / inositol polyphosphate phosphatase like 1* / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 *	ENSDARG00000104222	32
synj1 / synaptojanin 1 / O43426*	ENSDARG00000025011	15
ocrl / oculocerebrorenal syndrome of Lowe / Q01968* / Q6NVF0* / OCRL, inositol polyphosphate-5-phosphatase* / Inositol polyphosphate 5-phosphatase OCRL-1 *	ENSDARG00000078106	13
inpp5b / inositol polyphosphate-5-phosphatase B / P32019* / Q8K337* / Type II inositol 1,4,5-trisphosphate 5-phosphatase *	ENSDARG00000103683	12
inpp5e / inositol polyphosphate-5-phosphatase E / Q9JII1* / Q9NRR6* / 72 kDa inositol polyphosphate 5-phosphatase *	ENSDARG00000103926	10
inpp5kb / inositol polyphosphate-5-phosphatase Kb / INPP5K* / Q9BT40* / Q8C5L6* / inositol polyphosphate-5-phosphatase K*	ENSDARG00000078618	9
inpp5jb / inositol polyphosphate-5-phosphatase Jb / INPP5J* / P59644* / Q15735* / inositol polyphosphate-5-phosphatase J* / Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A *	ENSDARG00000093359	9
inpp5ja / inositol polyphosphate-5-phosphatase Ja / INPP5J* / P59644* / Q15735* / inositol polyphosphate-5-phosphatase J* / Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A *	ENSDARG00000078542	9
inpp5ka / inositol polyphosphate-5-phosphatase Ka / INPP5K* / Q9BT40* / Q8C5L6* / inositol polyphosphate-5-phosphatase K*	ENSDARG00000099563	8

Protein motifs (from Interpro)

Interpro ID	Name
IPR000300	Inositol polyphosphate-related phosphatase
IPR000980	SH2 domain
IPR005135	Endonuclease/exonuclease/phosphatase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0046856	phosphatidylinositol dephosphorylation	IEA
biological_process	GO:0090024	negative regulation of neutrophil chemotaxis	IGI
molecular_function	GO:0016787	hydrolase activity	IEA

Pathways (from Reactome)

Pathway description

Synthesis of PIPs at the plasma membrane

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0001094	whole organism	whole organism neutrophil decreased amount , abnormal	Show
ZFA:0009327	neutrophil	neutrophil increased cellular motility , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000075437	shc1 / SHC (Src homology 2 domain containing) transforming protein 1 / P98083* / P29353* / SHC adaptor protein 1* / SHC-transforming protein 1 *	/ reaction / complex
ENSDARG00000104808	jak2a / Janus kinase 2a / JAK2* / O60674* / Janus kinase 2*	/ reaction / complex
ENSDARG00000074283	inpp5d / inositol polyphosphate-5-phosphatase D / Q92835* / Q9ES52* / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 *	/ complex / reaction
ENSDARG00000018882	jak2b / Janus kinase 2b / JAK2* / O60674* / Janus kinase 2*	/ reaction / complex

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr