ENSDARG00000109726


Danio rerio

Features
Gene ID: ENSDARG00000109726
  
Biological name :PLCB1
  
Synonyms : PLCB1 / si:ch1073-140o9.2
  
Possible biological names infered from orthology : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 / phospholipase C beta 1 / Q9NQ66 / Q9Z1B3
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 3841012
Gene end: 3986236
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000141334
Ensembl peptide - ENSDARP00000153275
swissprot - A0A0R4IY65
ZFIN ID - ZDB-GENE-120709-104
Ensembl - ENSDARG00000109726
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLCB1ENSGALG00000008875Gallus gallus
 PLCB1ENSG00000182621Homo sapiens
 Plcb1ENSMUSG00000051177Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
plcb3 / phospholipase C, beta 3 (phosphatidylinositol-specific) / P51432* / Q01970* / phospholipase C beta 3*ENSDARG0000006824646
PLCB4 / phospholipase C beta 4 / Q15147*ENSDARG0000010078629
plch2a / phospholipase C, eta 2a / PLCH2* / A2AP18* / O75038* / phospholipase C eta 2* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 *ENSDARG0000005996018
plch1 / phospholipase C, eta 1 / Q4KWH5* / Q4KWH8* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 *ENSDARG0000007925318
plcl2 / phospholipase C like 2 / Q8K394* / Q9UPR0* / Inactive phospholipase C-like protein 2 *ENSDARG0000009882618
PLCB2 / phospholipase C beta 2 / A3KGF7* / Q00722* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 *ENSDARG0000009038117
plcl1 / phospholipase C like 1 / Q15111* / Q3USB7* / phospholipase C like 1 (inactive)* / Inactive phospholipase C-like protein 1 *ENSDARG0000006767617
si:ch211-210g13.5ENSDARG0000006257517
plcd3b / phospholipase C, delta 3b / PLCD3* / Q8N3E9* / Q8K2J0* / phospholipase C delta 3* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 *ENSDARG0000007957216
plcd1a / phospholipase C, delta 1a / PLCD1* / Q8R3B1* / P51178* / phospholipase C delta 1* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 *ENSDARG0000005912315
plcd4b / phospholipase C, delta 4b / PLCD4* / Q8K3R3* / Q9BRC7* / phospholipase C delta 4*ENSDARG0000004068415
plcd1b / phospholipase C, delta 1b / PLCD1* / P51178* / phospholipase C delta 1*ENSDARG0000003408015
A5D6R3 / plcd3a / phospholipase C, delta 3a / PLCD3* / Q8N3E9* / Q8K2J0* / phospholipase C delta 3* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 *ENSDARG0000005295715
plcd4a / phospholipase C, delta 4a / PLCD4* / Q8K3R3* / Q9BRC7* / phospholipase C delta 4*ENSDARG0000005797515
plch2b / phospholipase C, eta 2b / PLCH2* / A2AP18* / O75038* / phospholipase C eta 2* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 *ENSDARG0000005680514


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000909  Phosphatidylinositol-specific phospholipase C, X domain
 IPR001192  Phosphoinositide phospholipase C family
 IPR009535  Phospholipase C-beta, conserved site
 IPR011992  EF-hand domain pair
 IPR011993  PH-like domain superfamily
 IPR014815  Phospholipase C-beta, C-terminal domain
 IPR015359  Phosphoinositide-specific phospholipase C, EF-hand-like domain
 IPR016280  Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta
 IPR017946  PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
 IPR028400  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
PLC beta mediated events
Synthesis of IP3 and IP4 in the cytosol
Ca2+ pathway
G alpha (q) signalling events
G beta:gamma signalling through PLC beta
Presynaptic function of Kainate receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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