ENSG00000006116


Homo sapiens

Features
Gene ID: ENSG00000006116
  
Biological name :CACNG3
  
Synonyms : CACNG3 / calcium voltage-gated channel auxiliary subunit gamma 3 / O60359
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p12.1
Gene start: 24255553
Gene end: 24362801
  
Corresponding Affymetrix probe sets: 206384_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000005284
NCBI entrez gene - 10368     See in Manteia.
OMIM - 606403
RefSeq - NM_006539
RefSeq Peptide - NP_006530
swissprot - O60359
Ensembl - ENSG00000006116
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cacng3aENSDARG00000058460Danio rerio
 cacng3bENSDARG00000076401Danio rerio
 CACNG3ENSGALG00000038087Gallus gallus
 Cacng3ENSMUSG00000066189Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CACNG2 / Q9Y698 / calcium voltage-gated channel auxiliary subunit gamma 2ENSG0000016686277
CACNG8 / Q8WXS5 / calcium voltage-gated channel auxiliary subunit gamma 8ENSG0000014240860
CACNG4 / Q9UBN1 / calcium voltage-gated channel auxiliary subunit gamma 4ENSG0000007546159
CACNG5 / Q9UF02 / calcium voltage-gated channel auxiliary subunit gamma 5ENSG0000007542925
CACNG7 / P62955 / calcium voltage-gated channel auxiliary subunit gamma 7ENSG0000010560525


Protein motifs (from Interpro)
Interpro ID Name
 IPR004031  PMP-22/EMP/MP20/Claudin superfamily
 IPR008368  Voltage-dependent calcium channel, gamma subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006605 protein targeting IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport NAS
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0019226 transmission of nerve impulse IBA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0061337 cardiac conduction TAS
 biological_processGO:0070588 calcium ion transmembrane transport IBA
 biological_processGO:2000311 regulation of AMPA receptor activity IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005891 voltage-gated calcium channel complex NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 cellular_componentGO:0032281 AMPA glutamate receptor complex IEA
 cellular_componentGO:0036477 somatodendritic compartment IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005245 voltage-gated calcium channel activity IBA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0016247 channel regulator activity IBA


Pathways (from Reactome)
Pathway description
Trafficking of AMPA receptors
Phase 0 - rapid depolarisation
Phase 2 - plateau phase
LGI-ADAM interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000114948 ADAM23 / O75077 / ADAM metallopeptidase domain 23  / complex / reaction
 ENSG00000008277 ADAM22 / Q9P0K1 / ADAM metallopeptidase domain 22  / complex
 ENSG00000132535 DLG4 / P78352 / discs large MAGUK scaffold protein 4  / complex
 ENSG00000135679 MDM2 / Q00987 / MDM2 proto-oncogene  / complex
 ENSG00000108231 LGI1 / O95970 / leucine rich glioma inactivated 1  / complex / reaction






 

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