ENSG00000006831


Homo sapiens

Features
Gene ID: ENSG00000006831
  
Biological name :ADIPOR2
  
Synonyms : adiponectin receptor 2 / ADIPOR2 / Q86V24
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p13.33
Gene start: 1688574
Gene end: 1788678
  
Corresponding Affymetrix probe sets: 201346_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000349616
NCBI entrez gene - 79602     See in Manteia.
OMIM - 607946
RefSeq - XM_011521024
RefSeq - NM_024551
RefSeq - XM_005253789
RefSeq - XM_006719018
RefSeq Peptide - NP_078827
swissprot - Q86V24
Ensembl - ENSG00000006831
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adipor2ENSDARG00000101849Danio rerio
 ADIPOR2ENSGALG00000035533Gallus gallus
 Q8BQS5ENSMUSG00000030168Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96A54 / ADIPOR1 / adiponectin receptor 1ENSG0000015934667
PAQR3 / Q6TCH7 / progestin and adipoQ receptor family member 3ENSG0000016329122
PAQR4 / Q8N4S7 / progestin and adipoQ receptor family member 4ENSG0000016207319


Protein motifs (from Interpro)
Interpro ID Name
 IPR004254  AdipoR/Haemolysin-III-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0007584 response to nutrient IEA
 biological_processGO:0009755 hormone-mediated signaling pathway ISS
 biological_processGO:0019395 fatty acid oxidation ISS
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0033211 adiponectin-activated signaling pathway IDA
 biological_processGO:0042304 regulation of fatty acid biosynthetic process TAS
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0046326 positive regulation of glucose import IEA
 biological_processGO:0061042 vascular wound healing IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031226 intrinsic component of plasma membrane IDA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0055100 adiponectin binding IDA
 molecular_functionGO:0097003 adipokinetic hormone receptor activity IDA


Pathways (from Reactome)
Pathway description
AMPK inhibits chREBP transcriptional activation activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000181092 ADIPOQ / Q15848 / adiponectin, C1Q and collagen domain containing  / complex / reaction
 ENSG00000159346 Q96A54 / ADIPOR1 / adiponectin receptor 1  / complex
 ENSG00000006831 Q86V24 / ADIPOR2 / adiponectin receptor 2  / complex






 

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