ENSG00000159346


Homo sapiens

Features
Gene ID: ENSG00000159346
  
Biological name :ADIPOR1
  
Synonyms : adiponectin receptor 1 / ADIPOR1 / Q96A54
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q32.1
Gene start: 202940823
Gene end: 202958572
  
Corresponding Affymetrix probe sets: 217748_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000392946
Ensembl peptide - ENSP00000402178
Ensembl peptide - ENSP00000341785
Ensembl peptide - ENSP00000356223
NCBI entrez gene - 51094     See in Manteia.
OMIM - 607945
RefSeq - XM_017001407
RefSeq - NM_001290553
RefSeq - NM_001290557
RefSeq - NM_001290629
RefSeq - NM_015999
RefSeq Peptide - NP_001277482
RefSeq Peptide - NP_001277486
RefSeq Peptide - NP_001277558
RefSeq Peptide - NP_057083
swissprot - C9JNM5
swissprot - C9J0W7
swissprot - Q96A54
swissprot - F8W782
Ensembl - ENSG00000159346
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adipor1aENSDARG00000002912Danio rerio
 adipor1bENSDARG00000042717Danio rerio
 ADIPOR1ENSGALG00000000094Gallus gallus
 Q91VH1ENSMUSG00000026457Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q86V24 / ADIPOR2 / adiponectin receptor 2ENSG0000000683169
PAQR3 / Q6TCH7 / progestin and adipoQ receptor family member 3ENSG0000016329126
PAQR4 / Q8N4S7 / progestin and adipoQ receptor family member 4ENSG0000016207321


Protein motifs (from Interpro)
Interpro ID Name
 IPR004254  AdipoR/Haemolysin-III-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0009755 hormone-mediated signaling pathway IDA
 biological_processGO:0010633 negative regulation of epithelial cell migration IMP
 biological_processGO:0010719 negative regulation of epithelial to mesenchymal transition IMP
 biological_processGO:0010906 regulation of glucose metabolic process IEA
 biological_processGO:0019216 regulation of lipid metabolic process IEA
 biological_processGO:0019395 fatty acid oxidation IDA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0033210 leptin-mediated signaling pathway IEA
 biological_processGO:0033211 adiponectin-activated signaling pathway IEA
 biological_processGO:0042304 regulation of fatty acid biosynthetic process TAS
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IMP
 biological_processGO:0046427 positive regulation of JAK-STAT cascade IEA
 biological_processGO:0046628 positive regulation of insulin receptor signaling pathway IEA
 biological_processGO:1901223 negative regulation of NIK/NF-kappaB signaling IMP
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031226 intrinsic component of plasma membrane IDA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0055100 adiponectin binding IEA
 molecular_functionGO:0097003 adipokinetic hormone receptor activity IDA


Pathways (from Reactome)
Pathway description
AMPK inhibits chREBP transcriptional activation activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000159346 Q96A54 / ADIPOR1 / adiponectin receptor 1  / complex
 ENSG00000181092 ADIPOQ / Q15848 / adiponectin, C1Q and collagen domain containing  / complex / reaction
 ENSG00000006831 Q86V24 / ADIPOR2 / adiponectin receptor 2  / complex






 

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