ENSG00000163291


Homo sapiens

Features
Gene ID: ENSG00000163291
  
Biological name :PAQR3
  
Synonyms : PAQR3 / progestin and adipoQ receptor family member 3 / Q6TCH7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q21.21
Gene start: 78887127
Gene end: 78939438
  
Corresponding Affymetrix probe sets: 1557576_at (Human Genome U133 Plus 2.0 Array)   213372_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000422357
Ensembl peptide - ENSP00000426875
Ensembl peptide - ENSP00000425080
Ensembl peptide - ENSP00000344203
Ensembl peptide - ENSP00000378959
Ensembl peptide - ENSP00000420848
Ensembl peptide - ENSP00000421981
NCBI entrez gene - 152559     See in Manteia.
OMIM - 614577
RefSeq - XM_005262769
RefSeq - XM_017007785
RefSeq - NM_001040202
RefSeq Peptide - NP_001035292
swissprot - Q6TCH7
swissprot - D6RDU4
swissprot - F8W784
Ensembl - ENSG00000163291
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 paqr3aENSDARG00000017703Danio rerio
 paqr3bENSDARG00000044253Danio rerio
 PAQR3ENSGALG00000010886Gallus gallus
 Paqr3ENSMUSG00000055725Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96A54 / ADIPOR1 / adiponectin receptor 1ENSG0000015934631
Q86V24 / ADIPOR2 / adiponectin receptor 2ENSG0000000683127
PAQR4 / Q8N4S7 / progestin and adipoQ receptor family member 4ENSG0000016207320


Protein motifs (from Interpro)
Interpro ID Name
 IPR004254  AdipoR/Haemolysin-III-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0001933 negative regulation of protein phosphorylation IDA
 biological_processGO:0010977 negative regulation of neuron projection development IDA
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IDA
 biological_processGO:0034067 protein localization to Golgi apparatus IPI
 biological_processGO:0043407 negative regulation of MAP kinase activity IDA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Negative regulation of MAPK pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000157764 BRAF / P15056 / B-Raf proto-oncogene, serine/threonine kinase  / complex / reaction
 ENSG00000132155 RAF1 / P04049 / Raf-1 proto-oncogene, serine/threonine kinase  / complex / reaction
 ENSG00000078061 ARAF / P10398 / A-Raf proto-oncogene, serine/threonine kinase  / reaction / complex






 

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