ENSMUSG00000055725


Mus musculus

Features
Gene ID: ENSMUSG00000055725
  
Biological name :Paqr3
  
Synonyms : Paqr3 / progestin and adipoQ receptor family member III / Q6TCG8
  
Possible biological names infered from orthology : progestin and adipoQ receptor family member 3 / Q6TCH7
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: E3
Gene start: 97082329
Gene end: 97111596
  
Corresponding Affymetrix probe sets: 10531544 (MoGene1.0st)   1429216_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000108593
Ensembl peptide - ENSMUSP00000142871
Ensembl peptide - ENSMUSP00000069324
Ensembl peptide - ENSMUSP00000108592
NCBI entrez gene - 231474     See in Manteia.
MGI - MGI:2679683
RefSeq - XM_006534874
RefSeq - XM_006534875
RefSeq - XM_006534876
RefSeq - NM_198422
RefSeq Peptide - NP_940814
swissprot - Q0VAZ2
swissprot - A0A0G2JER4
swissprot - D3Z181
swissprot - Q6TCG8
Ensembl - ENSMUSG00000055725
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 paqr3aENSDARG00000017703Danio rerio
 paqr3bENSDARG00000044253Danio rerio
 PAQR3ENSGALG00000010886Gallus gallus
 PAQR3ENSG00000163291Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q91VH1 / Adipor1 / adiponectin receptor 1 / Q96A54*ENSMUSG0000002645732
Q8BQS5 / Adipor2 / adiponectin receptor 2 / Q86V24*ENSMUSG0000003016827
Paqr4 / Q9JJE4 / Progestin and adipoQ receptor family member 4 / Q8N4S7*ENSMUSG0000002390920


Protein motifs (from Interpro)
Interpro ID Name
 IPR004254  AdipoR/Haemolysin-III-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0010977 negative regulation of neuron projection development IEA
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0034067 protein localization to Golgi apparatus IEA
 biological_processGO:0043407 negative regulation of MAP kinase activity IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Negative regulation of MAPK pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001219 thickened epidermis "increase in the width of the epidermal cell layer in the skin" [J:65146]
Show

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor

 MP:0002038 carcinoma "malignant neoplasm arising from epithelial cells, usually glandular or squamous" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877]
Show

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor

 MP:0002051 skin papilloma "a circumscribed, benign epithelial tumor projecting from the surrounding surface" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Paqr3tm1Ychn/Paqr3+
Genetic Background: involves: 129 * C57BL/6J

 MP:0003721 increased tumor growth/size "greater than expected development of tumorous growth when compared to controls" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor

 MP:0004499 increased incidence of chemically-induced tumors "higher than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Paqr3tm1Ychn/Paqr3+
Genetic Background: involves: 129 * C57BL/6J

 MP:0009583 increased keratinocyte proliferation "increase in the expansion rate of keratinocytes by cell division" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dbhtm2(Th)Rpa/Dbh+,Thtm5Rpa/Thtm5Rpa
Genetic Background: involves: 129S4/SvJaeSor

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000001127 Araf / P04627 / Serine/threonine-protein kinase A-Raf / P10398* / A-Raf proto-oncogene, serine/threonine kinase*  / reaction / complex
 ENSMUSG00000002413 Braf / P28028 / Serine/threonine-protein kinase B-raf / P15056* / B-Raf proto-oncogene, serine/threonine kinase*  / complex / reaction
 ENSMUSG00000000441 Raf1 / Q99N57 / Mus musculus v-raf-leukemia viral onco 1 (Raf1), transcript variant 3, mRNA. / P04049* / Raf-1 proto-oncogene, serine/threonine kinase*  / complex / reaction






 

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