ENSG00000011454


Homo sapiens

Features
Gene ID: ENSG00000011454
  
Biological name :RABGAP1
  
Synonyms : Q9Y3P9 / RABGAP1 / RAB GTPase activating protein 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q33.2
Gene start: 122940833
Gene end: 123104866
  
Corresponding Affymetrix probe sets: 204028_s_at (Human Genome U133 Plus 2.0 Array)   213313_at (Human Genome U133 Plus 2.0 Array)   215070_x_at (Human Genome U133 Plus 2.0 Array)   221294_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000416327
Ensembl peptide - ENSP00000482287
Ensembl peptide - ENSP00000362751
Ensembl peptide - ENSP00000384119
Ensembl peptide - ENSP00000414386
NCBI entrez gene - 2844     See in Manteia.
NCBI entrez gene - 23637     See in Manteia.
OMIM - 601909
OMIM - 615882
RefSeq - XM_017014570
RefSeq - XM_011518441
RefSeq - XM_011518442
RefSeq - XM_011518444
RefSeq - XM_017014567
RefSeq - XM_017014568
RefSeq - XM_017014569
RefSeq - NM_005294
RefSeq - NM_012197
RefSeq - XM_005251933
RefSeq - XM_011518440
RefSeq Peptide - NP_005285
RefSeq Peptide - NP_036329
swissprot - C9JGR5
swissprot - H9NIL4
swissprot - Q9Y3P9
swissprot - B5MCD9
Ensembl - ENSG00000011454
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rabgap1ENSDARG00000098967Danio rerio
 RABGAP1ENSGALG00000001225Gallus gallus
 A2AWA9ENSMUSG00000035437Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
B7ZAP0 / Q5R372 / RABGAP1L / RAB GTPase activating protein 1 likeENSG0000015206150
O60343 / TBC1D4 / TBC1 domain family member 4ENSG0000013611121
Q86TI0 / TBC1D1 / TBC1 domain family member 1ENSG0000006588220
EVI5 / O60447 / ecotropic viral integration site 5ENSG0000006720819
EVI5L / Q96CN4 / ecotropic viral integration site 5 likeENSG0000014245917
Q9P2M4 / TBC1D14 / TBC1 domain family member 14ENSG0000013240512
O60347 / TBC1D12 / TBC1 domain family member 12ENSG0000010823910


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR022164  Kinesin-like
 IPR033185  Rab GTPase-activating protein 1
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0043087 regulation of GTPase activity IDA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome TAS
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005875 microtubule associated complex TAS
 cellular_componentGO:0012505 endomembrane system IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015631 tubulin binding TAS
 molecular_functionGO:0017137 Rab GTPase binding IPI


Pathways (from Reactome)
Pathway description
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000175582 RAB6A / P20340 / RAB6A, member RAS oncogene family  / reaction / complex






 

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