ENSMUSG00000035437


Mus musculus

Features
Gene ID: ENSMUSG00000035437
  
Biological name :Rabgap1
  
Synonyms : A2AWA9 / Rabgap1 / RAB GTPase activating protein 1
  
Possible biological names infered from orthology : Q9Y3P9
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: B
Gene start: 37443279
Gene end: 37566454
  
Corresponding Affymetrix probe sets: 10471784 (MoGene1.0st)   1424188_at (Mouse Genome 430 2.0 Array)   1441555_at (Mouse Genome 430 2.0 Array)   1441800_at (Mouse Genome 430 2.0 Array)   1443535_at (Mouse Genome 430 2.0 Array)   1460486_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000061624
Ensembl peptide - ENSMUSP00000121963
Ensembl peptide - ENSMUSP00000119831
Ensembl peptide - ENSMUSP00000108542
Ensembl peptide - ENSMUSP00000068835
NCBI entrez gene - 227800     See in Manteia.
MGI - MGI:2385139
RefSeq - XM_006497997
RefSeq - NM_001033960
RefSeq - NM_146121
RefSeq - XM_006497994
RefSeq - XM_006497995
RefSeq - XM_006497996
RefSeq Peptide - NP_001029132
RefSeq Peptide - NP_666233
swissprot - A2AWA9
swissprot - A2AWA7
swissprot - A2AWB0
swissprot - B2RRC5
Ensembl - ENSMUSG00000035437
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rabgap1ENSDARG00000098967Danio rerio
 RABGAP1ENSGALG00000001225Gallus gallus
 Q9Y3P9ENSG00000011454Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A6H6A9 / Rabgap1l / Rab GTPase-activating protein 1-like / B7ZAP0* / Q5R372*ENSMUSG0000002672150
Tbc1d4 / TBC1 domain family member 4 / O60343*ENSMUSG0000003308320
Q60949 / Tbc1d1 / TBC1 domain family, member 1 / Q86TI0*ENSMUSG0000002917420
Evi5 / ecotropic viral integration site 5 / O60447*ENSMUSG0000001183119
Evi5l / Mus musculus ecotropic viral integration site 5 like (Evi5l), transcript variant 2, mRNA. / Q96CN4* / ecotropic viral integration site 5 like*ENSMUSG0000001183217
Tbc1d14 / TBC1 domain family, member 14 / Q9P2M4*ENSMUSG0000002919212
Tbc1d12 / TBC1 domain family member 12 / O60347*ENSMUSG0000004872010


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR022164  Kinesin-like
 IPR033185  Rab GTPase-activating protein 1
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0012505 endomembrane system IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017137 Rab GTPase binding IEA


Pathways (from Reactome)
Pathway description
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000030704 Rab6a / P35279 / RAB6A, member RAS oncogene family / RAB6C* / RAB6D* / Q9H0N0* / P20340* / RAB6C, member RAS oncogene family* / RAB6D, member RAS oncogene family*  / complex / reaction






 

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