ENSMUSG00000026721


Mus musculus

Features
Gene ID: ENSMUSG00000026721
  
Biological name :Rabgap1l
  
Synonyms : A6H6A9 / Rabgap1l / Rab GTPase-activating protein 1-like
  
Possible biological names infered from orthology : B7ZAP0 / Q5R372
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: H2.1
Gene start: 160219174
Gene end: 160793211
  
Corresponding Affymetrix probe sets: 10359339 (MoGene1.0st)   1421488_at (Mouse Genome 430 2.0 Array)   1429196_at (Mouse Genome 430 2.0 Array)   1429197_s_at (Mouse Genome 430 2.0 Array)   1434062_at (Mouse Genome 430 2.0 Array)   1453365_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028052
Ensembl peptide - ENSMUSP00000142258
Ensembl peptide - ENSMUSP00000141790
Ensembl peptide - ENSMUSP00000141749
Ensembl peptide - ENSMUSP00000141688
Ensembl peptide - ENSMUSP00000141666
Ensembl peptide - ENSMUSP00000141357
Ensembl peptide - ENSMUSP00000028049
NCBI entrez gene - 29809     See in Manteia.
MGI - MGI:1352507
RefSeq - XM_006496876
RefSeq - XM_006496882
RefSeq - XM_006496881
RefSeq - XM_006496879
RefSeq - XM_006496878
RefSeq - NM_001038621
RefSeq - NM_013862
RefSeq - XM_006496877
RefSeq - XM_006496875
RefSeq - XM_006496883
RefSeq Peptide - NP_001033710
RefSeq Peptide - NP_038890
swissprot - A6H6A9
swissprot - A0A0A6YW18
swissprot - A0A0A6YWT4
swissprot - A0A0A6YWY0
swissprot - A0A0A6YX13
swissprot - A0A0A6YY35
Ensembl - ENSMUSG00000026721
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rabgap1l2ENSDARG00000060315Danio rerio
 RABGAP1LENSGALG00000004578Gallus gallus
 B7ZAP0ENSG00000152061Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A2AWA9 / Rabgap1 / RAB GTPase activating protein 1 / Q9Y3P9*ENSMUSG0000003543765
Q60949 / Tbc1d1 / TBC1 domain family, member 1 / Q86TI0*ENSMUSG0000002917424
Tbc1d4 / TBC1 domain family member 4 / O60343*ENSMUSG0000003308323
Evi5 / ecotropic viral integration site 5 / O60447*ENSMUSG0000001183118
Evi5l / Mus musculus ecotropic viral integration site 5 like (Evi5l), transcript variant 2, mRNA. / Q96CN4* / ecotropic viral integration site 5 like*ENSMUSG0000001183217
Tbc1d14 / TBC1 domain family, member 14 / Q9P2M4*ENSMUSG0000002919215
Tbc1d12 / TBC1 domain family member 12 / O60347*ENSMUSG0000004872013


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR022164  Kinesin-like
 IPR033185  Rab GTPase-activating protein 1
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0032880 regulation of protein localization ISO
 biological_processGO:0035855 megakaryocyte development NAS
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0012505 endomembrane system IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017137 Rab GTPase binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Atrxtm1Rjg/Y,Tg(Nes-cre)2472Pick/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr