ENSG00000065882


Homo sapiens

Features
Gene ID: ENSG00000065882
  
Biological name :TBC1D1
  
Synonyms : Q86TI0 / TBC1D1 / TBC1 domain family member 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: p14
Gene start: 37891087
Gene end: 38139175
  
Corresponding Affymetrix probe sets: 1568713_a_at (Human Genome U133 Plus 2.0 Array)   1569566_at (Human Genome U133 Plus 2.0 Array)   212350_at (Human Genome U133 Plus 2.0 Array)   214013_s_at (Human Genome U133 Plus 2.0 Array)   227945_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000410167
Ensembl peptide - ENSP00000397640
Ensembl peptide - ENSP00000421641
Ensembl peptide - ENSP00000478039
Ensembl peptide - ENSP00000425655
Ensembl peptide - ENSP00000423651
Ensembl peptide - ENSP00000261439
Ensembl peptide - ENSP00000383994
Ensembl peptide - ENSP00000396877
NCBI entrez gene - 23216     See in Manteia.
OMIM - 609850
RefSeq - XM_017007922
RefSeq - XM_011513660
RefSeq - XM_011513662
RefSeq - XM_011513663
RefSeq - XM_011513664
RefSeq - XM_011513665
RefSeq - XM_011513666
RefSeq - XM_011513670
RefSeq - XM_017007918
RefSeq - XM_017007919
RefSeq - XM_017007920
RefSeq - XM_017007921
RefSeq - NM_001253912
RefSeq - NM_015173
RefSeq - XM_005262646
RefSeq - XM_005262647
RefSeq - XM_005262649
RefSeq - XM_006714001
RefSeq - XM_011513659
RefSeq Peptide - NP_001240841
RefSeq Peptide - NP_055988
swissprot - B5MCJ2
swissprot - H0Y8P0
swissprot - H0YA01
swissprot - C9JIE2
swissprot - H7C380
swissprot - Q86TI0
swissprot - A0JNU9
swissprot - H7C0Z7
swissprot - B9A6J6
Ensembl - ENSG00000065882
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tbc1d1ENSDARG00000062081Danio rerio
 TBC1D1ENSGALG00000039380Gallus gallus
 Q60949ENSMUSG00000029174Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O60343 / TBC1D4 / TBC1 domain family member 4ENSG0000013611152
Q9Y3P9 / RABGAP1 / RAB GTPase activating protein 1ENSG0000001145419
B7ZAP0 / Q5R372 / RABGAP1L / RAB GTPase activating protein 1 likeENSG0000015206117
Q9P2M4 / TBC1D14 / TBC1 domain family member 14ENSG0000013240512
EVI5L / Q96CN4 / ecotropic viral integration site 5 likeENSG0000014245911
EVI5 / O60447 / ecotropic viral integration site 5ENSG0000006720811
O60347 / TBC1D12 / TBC1 domain family member 12ENSG0000010823910


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR021785  Domain of unknown function DUF3350
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0032880 regulation of protein localization IEA
 biological_processGO:0061024 membrane organization TAS
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0012505 endomembrane system IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017137 Rab GTPase binding IBA


Pathways (from Reactome)
Pathway description
Translocation of SLC2A4 (GLUT4) to the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000162409 P54646 / PRKAA2 / protein kinase AMP-activated catalytic subunit alpha 2  / reaction






 

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