ENSG00000042493


Homo sapiens

Features
Gene ID: ENSG00000042493
  
Biological name :CAPG
  
Synonyms : CAPG / capping actin protein, gelsolin like / P40121
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p11.2
Gene start: 85394748
Gene end: 85418432
  
Corresponding Affymetrix probe sets: 201850_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000397381
Ensembl peptide - ENSP00000391923
Ensembl peptide - ENSP00000398232
Ensembl peptide - ENSP00000403330
Ensembl peptide - ENSP00000263867
Ensembl peptide - ENSP00000386315
Ensembl peptide - ENSP00000386596
Ensembl peptide - ENSP00000386965
Ensembl peptide - ENSP00000387063
NCBI entrez gene - 822     See in Manteia.
OMIM - 153615
RefSeq - XM_011533123
RefSeq - NM_001256139
RefSeq - NM_001256140
RefSeq - NM_001320732
RefSeq - NM_001320733
RefSeq - NM_001320734
RefSeq - NM_001747
RefSeq - XM_011533122
RefSeq Peptide - NP_001307662
RefSeq Peptide - NP_001307663
RefSeq Peptide - NP_001738
RefSeq Peptide - NP_001307661
RefSeq Peptide - NP_001243068
RefSeq Peptide - NP_001243069
swissprot - V9HW69
swissprot - E7ENU9
swissprot - H7C0X8
swissprot - P40121
swissprot - B8ZZL6
Ensembl - ENSG00000042493
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 capgaENSDARG00000035560Danio rerio
 capgbENSDARG00000099672Danio rerio
 CapgENSMUSG00000056737Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GSN / P06396 / gelsolinENSG0000014818049
SCIN / Q9Y6U3 / scinderinENSG0000000674747
AVIL / O75366 / advillinENSG0000013540742
VIL1 / P09327 / villin 1ENSG0000012783142
VILL / O15195 / villin likeENSG0000013605936
FLII / Q13045 / FLII, actin remodeling proteinENSG0000017773130
SVIL / O95425 / supervillinENSG0000019732126


Protein motifs (from Interpro)
Interpro ID Name
 IPR007122  Villin/Gelsolin
 IPR007123  Gelsolin-like domain
 IPR029006  ADF-H/Gelsolin-like domain superfamily
 IPR029917  Macrophage-capping protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0051016 barbed-end actin filament capping IEA
 biological_processGO:0051693 actin filament capping IEA
 biological_processGO:0065003 protein-containing complex assembly NAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005814 centriole IDA
 cellular_componentGO:0008290 F-actin capping protein complex TAS
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0072686 mitotic spindle IDA
 cellular_componentGO:0090543 Flemming body IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0044877 protein-containing complex binding IDA
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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