ENSG00000197321


Homo sapiens

Features
Gene ID: ENSG00000197321
  
Biological name :SVIL
  
Synonyms : O95425 / supervillin / SVIL
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: p11.23
Gene start: 29457338
Gene end: 29736781
  
Corresponding Affymetrix probe sets: 202565_s_at (Human Genome U133 Plus 2.0 Array)   202566_s_at (Human Genome U133 Plus 2.0 Array)   217634_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000488171
Ensembl peptide - ENSP00000348128
Ensembl peptide - ENSP00000364547
Ensembl peptide - ENSP00000364549
NCBI entrez gene - 6840     See in Manteia.
OMIM - 604126
RefSeq - XM_017016582
RefSeq - NM_001323599
RefSeq - NM_001323600
RefSeq - NM_003174
RefSeq - NM_021738
RefSeq - XM_017016576
RefSeq - XM_017016577
RefSeq - XM_017016578
RefSeq - XM_017016579
RefSeq - XM_017016580
RefSeq - XM_017016581
RefSeq - XM_005252570
RefSeq - XM_005252571
RefSeq - XM_005252573
RefSeq - XM_011519630
RefSeq - XM_011519631
RefSeq - XM_011519632
RefSeq - XM_011519633
RefSeq - XM_011519634
RefSeq - XM_011519635
RefSeq - XM_011519636
RefSeq - XM_011519637
RefSeq - XM_011519638
RefSeq - XM_017016575
RefSeq Peptide - NP_001310528
RefSeq Peptide - NP_001310529
RefSeq Peptide - NP_003165
RefSeq Peptide - NP_068506
swissprot - O95425
swissprot - A0A0J9YWY6
Ensembl - ENSG00000197321
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 svilaENSDARG00000055075Danio rerio
 SVILENSGALG00000007331Gallus gallus
 SvilENSMUSG00000024236Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FLII / Q13045 / FLII, actin remodeling proteinENSG0000017773111
VILL / O15195 / villin likeENSG0000013605910
AVIL / O75366 / advillinENSG0000013540710
VIL1 / P09327 / villin 1ENSG0000012783110
SCIN / Q9Y6U3 / scinderinENSG000000067479
GSN / P06396 / gelsolinENSG000001481809
CAPG / P40121 / capping actin protein, gelsolin likeENSG000000424934


Protein motifs (from Interpro)
Interpro ID Name
 IPR003128  Villin headpiece
 IPR007122  Villin/Gelsolin
 IPR007123  Gelsolin-like domain
 IPR015628  Supervillin
 IPR029006  ADF-H/Gelsolin-like domain superfamily
 IPR036886  Villin headpiece domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007519 skeletal muscle tissue development IMP
 biological_processGO:0032467 positive regulation of cytokinesis ISS
 cellular_componentGO:0002102 podosome IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0015629 actin cytoskeleton NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030496 midbody ISS
 cellular_componentGO:0032154 cleavage furrow ISS
 cellular_componentGO:0036449 microtubule minus-end ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043034 costamere IDA
 cellular_componentGO:0071437 invadopodium IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0051015 actin filament binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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