ENSG00000050344


Homo sapiens

Features
Gene ID: ENSG00000050344
  
Biological name :NFE2L3
  
Synonyms : NFE2L3 / nuclear factor, erythroid 2 like 3 / Q9Y4A8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p15.2
Gene start: 26152240
Gene end: 26187125
  
Corresponding Affymetrix probe sets: 204702_s_at (Human Genome U133 Plus 2.0 Array)   236471_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000056233
Ensembl peptide - ENSP00000475463
NCBI entrez gene - 9603     See in Manteia.
OMIM - 604135
RefSeq - NM_004289
RefSeq Peptide - NP_004280
swissprot - Q9Y4A8
swissprot - U3KQ19
Ensembl - ENSG00000050344
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nfe2l3ENSDARG00000019810Danio rerio
 Nfe2l3ENSMUSG00000029832Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NFE2L1 / Q14494 / nuclear factor, erythroid 2 like 1ENSG0000008264137
NFE2L2 / Q16236 / nuclear factor, erythroid 2 like 2ENSG0000011604420
NFE2 / Q16621 / nuclear factor, erythroid 2ENSG0000012340517
BACH1 / O14867 / BTB domain and CNC homolog 1ENSG0000015627315
BACH2 / Q9BYV9 / BTB domain and CNC homolog 2ENSG0000011218214


Protein motifs (from Interpro)
Interpro ID Name
 IPR004826  Basic leucine zipper domain, Maf-type
 IPR004827  Basic-leucine zipper domain
 IPR008917  Transcription factor, Skn-1-like, DNA-binding domain superfamily
 IPR029854  Nuclear factor erythroid 2-related factor 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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