ENSMUSG00000029832


Mus musculus

Features
Gene ID: ENSMUSG00000029832
  
Biological name :Nfe2l3
  
Synonyms : Nfe2l3 / nuclear factor, erythroid derived 2, like 3 / Q9WTM4
  
Possible biological names infered from orthology : nuclear factor, erythroid 2 like 3 / Q9Y4A8
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: B3
Gene start: 51432670
Gene end: 51458768
  
Corresponding Affymetrix probe sets: 10538275 (MoGene1.0st)   1417520_at (Mouse Genome 430 2.0 Array)   1453614_a_at (Mouse Genome 430 2.0 Array)   1454240_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000124920
Ensembl peptide - ENSMUSP00000005103
NCBI entrez gene - 18025     See in Manteia.
MGI - MGI:1339958
RefSeq - NM_010903
RefSeq Peptide - NP_035033
swissprot - E9PWE6
swissprot - Q3UZC1
swissprot - Q9WTM4
Ensembl - ENSMUSG00000029832
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nfe2l3ENSDARG00000019810Danio rerio
 NFE2L3ENSG00000050344Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nfe2l1 / Q61985 / Nuclear factor erythroid 2-related factor 1 / Q14494* / nuclear factor, erythroid 2 like 1*ENSMUSG0000003861534
Nfe2l2 / Q60795 / Nuclear factor erythroid 2-related factor 2 / Q16236* / nuclear factor, erythroid 2 like 2*ENSMUSG0000001583920
Nfe2 / nuclear factor, erythroid 2 / Q16621*ENSMUSG0000005879417
Bach1 / P97302 / Transcription regulator protein BACH1 / O14867* / BTB domain and CNC homolog 1*ENSMUSG0000002561215
Bach2 / P97303 / Transcription regulator protein BACH2 / Q9BYV9* / BTB domain and CNC homolog 2*ENSMUSG0000004027013


Protein motifs (from Interpro)
Interpro ID Name
 IPR004826  Basic leucine zipper domain, Maf-type
 IPR004827  Basic-leucine zipper domain
 IPR008917  Transcription factor, Skn-1-like, DNA-binding domain superfamily
 IPR029854  Nuclear factor erythroid 2-related factor 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nfe2l2tm1Ney/Nfe2l2tm1Ney,Nfe2l3tm1Vbl/Nfe2l3tm1Vbl
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Prnpc/Prnpc
Genetic Background: MAI/Pas

Allelic Composition: Nfe2l2tm1Ney/Nfe2l2tm1Ney,Nfe2l3tm1Vbl/Nfe2l3tm1Vbl
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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