Manteia

ENSMUSG00000040270

Mus musculus

Features

Gene ID:	ENSMUSG00000040270

Biological name :	Bach2

Synonyms :	Bach2 / P97303 / Transcription regulator protein BACH2

Possible biological names infered from orthology :	BTB domain and CNC homolog 2 / Q9BYV9

Species:	Mus musculus

Chr. number:	4
Strand:	1
Band:	A5
Gene start:	32238804
Gene end:	32586108

Corresponding Affymetrix probe sets:	10503695 (MoGene1.0st) 1436515_at (Mouse Genome 430 2.0 Array) 1437667_a_at (Mouse Genome 430 2.0 Array) 1445460_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000043693 Ensembl peptide - ENSMUSP00000103815 Ensembl peptide - ENSMUSP00000131592 NCBI entrez gene - 12014 See in Manteia. MGI - MGI:894679 RefSeq - XM_011249910 RefSeq - NM_001109661 RefSeq - XM_011249908 RefSeq - XM_011249909 RefSeq - XM_006537566 RefSeq - XM_006537567 RefSeq Peptide - NP_001103131 swissprot - P97303 Ensembl - ENSMUSG00000040270

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
bach2a	ENSDARG00000036569	Danio rerio
bach2b	ENSDARG00000004074	Danio rerio
BACH2	ENSGALG00000015605	Gallus gallus
BACH2	ENSG00000112182	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Bach1 / P97302 / Transcription regulator protein BACH1 / O14867* / BTB domain and CNC homolog 1*	ENSMUSG00000025612	31
Nfe2l2 / Q60795 / Nuclear factor erythroid 2-related factor 2 / Q16236* / nuclear factor, erythroid 2 like 2*	ENSMUSG00000015839	12
Nfe2l1 / Q61985 / Nuclear factor erythroid 2-related factor 1 / Q14494* / nuclear factor, erythroid 2 like 1*	ENSMUSG00000038615	11
Nfe2l3 / Q9WTM4 / nuclear factor, erythroid derived 2, like 3 / Q9Y4A8* / nuclear factor, erythroid 2 like 3*	ENSMUSG00000029832	10
Nfe2 / nuclear factor, erythroid 2 / Q16621*	ENSMUSG00000058794	8

Protein motifs (from Interpro)

Interpro ID	Name
IPR000210	BTB/POZ domain
IPR004826	Basic leucine zipper domain, Maf-type
IPR004827	Basic-leucine zipper domain
IPR008917	Transcription factor, Skn-1-like, DNA-binding domain superfamily
IPR011333	SKP1/BTB/POZ domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA
biological_process	GO:0006351	transcription, DNA-templated	IEA
biological_process	GO:0006355	regulation of transcription, DNA-templated	IDA
biological_process	GO:0016567	protein ubiquitination	IEA
biological_process	GO:0051170	import into nucleus	IMP
cellular_component	GO:0005634	nucleus	ISO
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005829	cytosol	ISO
cellular_component	GO:0031463	Cul3-RING ubiquitin ligase complex	IBA
molecular_function	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	IDA
molecular_function	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding	IDA
molecular_function	GO:0003677	DNA binding	IDA
molecular_function	GO:0003700	DNA-binding transcription factor activity	IDA
molecular_function	GO:0004842	ubiquitin-protein transferase activity	IBA
molecular_function	GO:0005515	protein binding	IPI

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000063	reduced bone density	"decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]	Show Allelic Composition: Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp,Gt(ROSA)26Sor^{tm1(rtTA,EGFP)Nagy}/Gt(ROSA)26Sor⁺,Pten^tm1Rdp/Pten^tm1Rdp,Tg(tetO-BRAFV600E)29Lc/0,Tg(Tyr-cre/ERT2)13Bos/0 Genetic Background:* involves: 129/Sv * C57BL/6J * FVB * SJL
MP:0000219	increased neutrophil count	"greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp,Gt(ROSA)26Sor^{tm1(rtTA,EGFP)Nagy}/Gt(ROSA)26Sor⁺,Pten^tm1Rdp/Pten^tm1Rdp,Tg(tetO-BRAFV600E)29Lc/0,Tg(Tyr-cre/ERT2)13Bos/0 Genetic Background:* involves: 129/Sv * C57BL/6J * FVB * SJL
MP:0000220	increased monocyte count	"greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp,Gt(ROSA)26Sor^{tm1(rtTA,EGFP)Nagy}/Gt(ROSA)26Sor⁺,Pten^tm1Rdp/Pten^tm1Rdp,Tg(tetO-BRAFV600E)29Lc/0,Tg(Tyr-cre/ERT2)13Bos/0 Genetic Background:* involves: 129/Sv * C57BL/6J * FVB * SJL
MP:0000694	spleen hypoplasia	"small size due to reduced cell number in the spleen" [J:43971]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified
MP:0001805	decreased IgG	"less than normal immunoglobulin class G level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified
MP:0001807	decreased IgA	"less than normal immunoglobulin class A level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified
MP:0002144	abnormal B lymphocyte development	"atypical production of or inability to produce mature B cells, and/or accumulation of B cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified
MP:0002459	abnormal B cell physiology	"abnormal function of B lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified
MP:0002494	increased IgM	"greater than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified Allelic Composition: Bach2^m2Anu/Bach2^m2Anu Genetic Background: C57BL/6NCrlAnu-Bach2^m2Anu
MP:0002727	decreased circulating insulin level	"less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0003795	abnormal bone structure		Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0004815	abnormal somatic hypermutation frequency	"any anomaly in the high frequency of programmed mutation that occurs in the gene segments encoding the variable regions of antibodies during the differentiation of individual B lymphocytes into antibody producing plasma cells " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified
MP:0004816	abnormal class switch recombination	"anomaly in the rearrangement of the heavy chain genes of differentiating B cells such that the initially encoded heavy chain IgM molecule is altered to one encoding IgG, IgA or IgE; normally, this allows the body to produce antibodies with different effector functions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified
MP:0005011	increased eosinophil count	"greater than normal eosinophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp,Gt(ROSA)26Sor^{tm1(rtTA,EGFP)Nagy}/Gt(ROSA)26Sor⁺,Pten^tm1Rdp/Pten^tm1Rdp,Tg(tetO-BRAFV600E)29Lc/0,Tg(Tyr-cre/ERT2)13Bos/0 Genetic Background:* involves: 129/Sv * C57BL/6J * FVB * SJL
MP:0005017	decreased B cell number	"fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified Allelic Composition: Bach2^m1Ccg/Bach2^m1Ccg Genetic Background: C57BL/6-Bach2^m1Ccg Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0005554	decreased circulating creatinine level	"less than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0008044	increased NK cell number	"greater number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0008074	increased CD4-positive T cell number	"greater number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0008179	absent germinal center B cells	"absence of rapidly cycling mature B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA), and are involved in T-dependent immune responses; germinal center B cells are found typically in the germinal centers of lymph nodes and spleen" [CL:0000844, GO:0002314, ISBN:0781735149]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified
MP:0008182	decreased marginal zone B cell number	"reduced number of CD23-negative, CD21-positive B cells of the marginal zone of the spleen expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL" [CL:0000845, ISBN:0781735149]	Show Allelic Composition: Bach2^m1Ccg/Bach2^m1Ccg Genetic Background: C57BL/6-Bach2^m1Ccg
MP:0008211	decreased mature B cell number	"reduced number of the mature form of B cells, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex" [CL:0000785, ISBN:0781735149]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified Allelic Composition: Bach2^m2Anu/Bach2^m2Anu Genetic Background: C57BL/6NCrlAnu-Bach2^m2Anu Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0008214	increased immature B cell number	"greater number of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Bach2^m2Anu/Bach2^m2Anu Genetic Background: C57BL/6NCrlAnu-Bach2^m2Anu
MP:0008347	decreased gamma-delta T cell number	"reduced number of immature or mature T cells expressing an gamma-delta T cell receptor complex" [CL:0000798, ISBN:0781735149]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0008495	decreased IgG1 level	"less than normal immunoglobulin class G1 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified
MP:0008496	decreased IgG2a level	"less than normal immunoglobulin class G2a level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified
MP:0008497	decreased IgG2b level	"less than normal immunoglobulin class G2b level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified
MP:0008498	decreased IgG3 level	"less than normal immunoglobulin class G3 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]	Show Allelic Composition: Prnp/Prnd^tm1Aag/Prnp/Prnd^tm1Aag Genetic Background: Not Specified
MP:0010124	decreased bone mineral content	"reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0010169	decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	"a reduction in the number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release" [ISBN:0781735149]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0010373	myeloid hyperplasia	"greater than normal number of nucleated cells of the myeloid lineage (a monocyte, granulocyte, or mast cell), found in blood or other tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Bach2^m1Ccg/Bach2^m1Ccg Genetic Background: C57BL/6-Bach2^m1Ccg
MP:0010844	increased effector memory CD4-positive, alpha-beta T cell number	"increased number of CD4-positive, alpha-beta memory T cells with the phenotype CCR7-negative, CD127-positive, CD45RO-positive, and CD25-negative" [CL:0000905, GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0010850	increased effector memory CD8-positive, alpha-beta T cell number	"increased number of CD8-positive, alpha beta memory T cells with the phenotype CCR7-negative, CD127-positive, CD45RO-positive, and CD25-negative" [CL:0000913, GO_REF:0000031, GOC:add, GOC:pam, PMID:20146720]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0010851	decreased effector memory CD8-positive, alpha-beta T cell number	"reduced number of CD8-positive, alpha beta memory T cells with the phenotype CCR7-negative, CD127-positive, CD45RO-positive, and CD25-negative" [CL:0000913, GO_REF:0000031, GOC:add, GOC:pam, PMID:20146720]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0012767	increased KLRG1-positive NK cell number	"increase in the number of KLRG1 positive NK cells that represent a maturation subset of NK cells and is linked to NK cell proliferation" [MGI:Annie_Speak, PMID:19479342]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0013025	increased Ly6C low monocyte number	"increase in the number of monocytes that express low levels of Ly6C and low MHC class II that represent a subset of patrolling monocytes" [MGI:Annie_Speak]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0013154	increased KLRG1+ CD8 alpha beta T cell number	"increase in the number of CD8+ alpha beta T cells that express KLRG1, a marker of effector and memory T cells" [MGI:csmith]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0013157	increased KLRG1+ CD4 alpha beta T cell number	"increase in the number of CD4+ alpha beta T cells that express KLRG1, a marker of effector/memory and regulatory T cells" [MGI:csmith]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0013424	increased KLRG1-positive gamma-delta T cell number	"increase in the number of gamma-delta T cells positive for KLRG1, a marker associated with activation" [IMPC:Saran, PMID:19479342]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0013430	increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number	"increase in the number of the CD4+, CD25+ alpha-beta regulatory T cells with a CD44+ CD62L- memory phenotype" [IMPC:Saran]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0013433	increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number	"increase in the number of KLRG1+ CD4+, CD25+, alpha-beta regulatory T cell number positive for KLRG1, a marker associated with activation" [IMPC:Saran, PMID:19479342]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0013435	decreased CD8-positive, naive alpha-beta T cell number	"reduction in the number of the naÃ¯ve regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions with a CD44-low CD62L+ phenotype" [IMPC:Saran]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0013514	increased memory-marker CD4-negative NK T cell number	"increase in the number of memory-marker CD4-negative NK T cells with a CD44+ CD62L- phenotype" [MGI:Saran]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0013517	increased KLRG1-positive CD4-negative NK T cell number	"increase in the number of KLRG1-positive CD4-negative NK T cells, a marker associated with activation" [MGI:Saran]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0013663	increased myeloid cell number	"greater than the expected number of cells of the myeloid lineage" [CL:0000763]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0013772	increased effector memory T-helper cell number	"increase in the number of CD4-positive alpha-beta T-helper cells with a CD44-positive, CD62L-negative memory phenotype" [MGI:Saran]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi
MP:0013775	increased KLRG1-positive T-helper cell number	"increase in the number of CD4-positive alpha-beta T-helper cells expressing KLRG1, a marker associated with activation" [MGI:Saran]	Show Allelic Composition: Bach2^{tm1a(EUCOMM)Wtsi}/Bach2^{tm1a(EUCOMM)Wtsi} Genetic Background: C57BL/6N-Bach2^{tm1a(EUCOMM)Wtsi}/Wtsi

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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