ENSG00000112182


Homo sapiens

Features
Gene ID: ENSG00000112182
  
Biological name :BACH2
  
Synonyms : BACH2 / BTB domain and CNC homolog 2 / Q9BYV9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q15
Gene start: 89926529
Gene end: 90296908
  
Corresponding Affymetrix probe sets: 221234_s_at (Human Genome U133 Plus 2.0 Array)   227173_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000345642
Ensembl peptide - ENSP00000257749
Ensembl peptide - ENSP00000397668
Ensembl peptide - ENSP00000437473
Ensembl peptide - ENSP00000384145
NCBI entrez gene - 60468     See in Manteia.
OMIM - 605394
RefSeq - XM_017011167
RefSeq - NM_001170794
RefSeq - NM_021813
RefSeq - XM_017011162
RefSeq - XM_017011164
RefSeq - XM_017011165
RefSeq - XM_017011166
RefSeq - XM_005248758
RefSeq - XM_005248759
RefSeq - XM_011536039
RefSeq - XM_011536040
RefSeq - XM_017011156
RefSeq - XM_017011157
RefSeq - XM_017011158
RefSeq - XM_017011159
RefSeq - XM_017011160
RefSeq - XM_017011161
RefSeq Peptide - NP_068585
RefSeq Peptide - NP_001164265
swissprot - Q7Z6Q0
swissprot - Q9BYV9
Ensembl - ENSG00000112182
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bach2aENSDARG00000036569Danio rerio
 bach2bENSDARG00000004074Danio rerio
 BACH2ENSGALG00000015605Gallus gallus
 Bach2ENSMUSG00000040270Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BACH1 / O14867 / BTB domain and CNC homolog 1ENSG0000015627332
NFE2L2 / Q16236 / nuclear factor, erythroid 2 like 2ENSG0000011604412
NFE2L1 / Q14494 / nuclear factor, erythroid 2 like 1ENSG0000008264112
NFE2L3 / Q9Y4A8 / nuclear factor, erythroid 2 like 3ENSG0000005034412
NFE2 / Q16621 / nuclear factor, erythroid 2ENSG000001234058


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR004826  Basic leucine zipper domain, Maf-type
 IPR004827  Basic-leucine zipper domain
 IPR008917  Transcription factor, Skn-1-like, DNA-binding domain superfamily
 IPR011333  SKP1/BTB/POZ domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0051170 import into nucleus ISS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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