ENSG00000156273


Homo sapiens

Features
Gene ID: ENSG00000156273
  
Biological name :BACH1
  
Synonyms : BACH1 / BTB domain and CNC homolog 1 / O14867
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: 1
Band: q21.3
Gene start: 29194071
Gene end: 29630751
  
Corresponding Affymetrix probe sets: 1552401_a_at (Human Genome U133 Plus 2.0 Array)   1553608_a_at (Human Genome U133 Plus 2.0 Array)   204194_at (Human Genome U133 Plus 2.0 Array)   210818_s_at (Human Genome U133 Plus 2.0 Array)   234938_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448663
Ensembl peptide - ENSP00000470673
Ensembl peptide - ENSP00000449383
Ensembl peptide - ENSP00000449316
Ensembl peptide - ENSP00000448982
Ensembl peptide - ENSP00000286800
Ensembl peptide - ENSP00000382805
Ensembl peptide - ENSP00000392202
Ensembl peptide - ENSP00000400576
Ensembl peptide - ENSP00000408605
Ensembl peptide - ENSP00000416569
Ensembl peptide - ENSP00000447332
NCBI entrez gene - 571     See in Manteia.
OMIM - 602751
RefSeq - NM_001186
RefSeq - NM_206866
RefSeq Peptide - NP_001177
RefSeq Peptide - NP_996749
swissprot - M0QZP0
swissprot - C9JMP6
swissprot - O14867
swissprot - C9IYR0
swissprot - C9IYH8
swissprot - F8VZL7
swissprot - H7C4B6
Ensembl - ENSG00000156273
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bach1aENSDARG00000062553Danio rerio
 bach1bENSDARG00000002196Danio rerio
 BACH1ENSGALG00000015828Gallus gallus
 Bach1ENSMUSG00000025612Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BACH2 / Q9BYV9 / BTB domain and CNC homolog 2ENSG0000011218237
NFE2L1 / Q14494 / nuclear factor, erythroid 2 like 1ENSG0000008264116
NFE2L2 / Q16236 / nuclear factor, erythroid 2 like 2ENSG0000011604414
NFE2L3 / Q9Y4A8 / nuclear factor, erythroid 2 like 3ENSG0000005034414
NFE2 / Q16621 / nuclear factor, erythroid 2ENSG0000012340510


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR004826  Basic leucine zipper domain, Maf-type
 IPR004827  Basic-leucine zipper domain
 IPR008917  Transcription factor, Skn-1-like, DNA-binding domain superfamily
 IPR011333  SKP1/BTB/POZ domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle IMP
 biological_processGO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle IMP
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006281 DNA repair IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm HDA
 cellular_componentGO:0005829 cytosol HDA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0020037 heme binding NAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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