ENSG00000051596


Homo sapiens

Features
Gene ID: ENSG00000051596
  
Biological name :THOC3
  
Synonyms : Q96J01 / THOC3 / THO complex 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q35.2
Gene start: 175917873
Gene end: 176034680
  
Corresponding Affymetrix probe sets: 224623_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000425781
Ensembl peptide - ENSP00000427029
Ensembl peptide - ENSP00000487428
Ensembl peptide - ENSP00000427267
Ensembl peptide - ENSP00000265097
Ensembl peptide - ENSP00000394166
Ensembl peptide - ENSP00000421082
Ensembl peptide - ENSP00000422243
Ensembl peptide - ENSP00000424967
Ensembl peptide - ENSP00000425039
NCBI entrez gene - 84321     See in Manteia.
OMIM - 606929
RefSeq - NM_032361
RefSeq - XM_017009985
RefSeq Peptide - NP_115737
swissprot - H0YA11
swissprot - H0YAG7
swissprot - D6RGZ2
swissprot - H7C0C5
swissprot - Q96J01
swissprot - H0YAJ0
swissprot - D6REC9
swissprot - H0Y9T1
Ensembl - ENSG00000051596
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 thoc3ENSDARG00000056517Danio rerio
 THOC3ENSGALG00000024172Gallus gallus
 Thoc3ENSMUSG00000025872Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BZK7 / TBL1XR1 / transducin beta like 1 X-linked receptor 1ENSG0000017756522
TBL1X / O60907 / transducin beta like 1 X-linkedENSG0000010184922
TBL1Y / Q9BQ87 / transducin beta like 1 Y-linkedENSG0000009237721


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR013979  Translation initiation factor, beta propellor-like domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR020472  G-protein beta WD-40 repeat
 IPR024977  Anaphase-promoting complex subunit 4, WD40 domain
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0031124 mRNA 3"-end processing TAS
 biological_processGO:0046784 viral mRNA export from host cell nucleus IDA
 biological_processGO:0051028 mRNA transport IEA
 cellular_componentGO:0000346 transcription export complex IDA
 cellular_componentGO:0000445 THO complex part of transcription export complex IDA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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