ENSG00000058063


Homo sapiens

Features
Gene ID: ENSG00000058063
  
Biological name :ATP11B
  
Synonyms : ATP11B / ATPase phospholipid transporting 11B (putative) / Q9Y2G3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q26.33
Gene start: 182793500
Gene end: 182921635
  
Corresponding Affymetrix probe sets: 1554556_a_at (Human Genome U133 Plus 2.0 Array)   1554557_at (Human Genome U133 Plus 2.0 Array)   1564063_a_at (Human Genome U133 Plus 2.0 Array)   1564064_a_at (Human Genome U133 Plus 2.0 Array)   212536_at (Human Genome U133 Plus 2.0 Array)   238811_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419152
Ensembl peptide - ENSP00000419032
Ensembl peptide - ENSP00000419768
Ensembl peptide - ENSP00000321195
Ensembl peptide - ENSP00000417124
Ensembl peptide - ENSP00000417406
Ensembl peptide - ENSP00000418421
NCBI entrez gene - 23200     See in Manteia.
OMIM - 605869
RefSeq - XM_017006009
RefSeq - NM_014616
RefSeq - XM_005247241
RefSeq - XM_005247243
RefSeq - XM_011512593
RefSeq - XM_011512594
RefSeq - XM_011512597
RefSeq - XM_017006008
RefSeq Peptide - NP_055431
swissprot - H0Y854
swissprot - H0Y8C7
swissprot - H7C4E6
swissprot - Q9Y2G3
swissprot - H7C575
swissprot - A0A0C4DG94
swissprot - H7C4W6
Ensembl - ENSG00000058063
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATP11BENSDARG00000101094Danio rerio
 ATP11BENSGALG00000008839Gallus gallus
 Atp11bENSMUSG00000037400Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATP11A / P98196 / ATPase phospholipid transporting 11AENSG0000006865056
ATP11C / Q8NB49 / ATPase phospholipid transporting 11CENSG0000010197452
ATP8A2 / Q9NTI2 / ATPase phospholipid transporting 8A2ENSG0000013293234
ATP8A1 / Q9Y2Q0 / ATPase phospholipid transporting 8A1ENSG0000012440634
ATP8B4 / Q8TF62 / ATPase phospholipid transporting 8B4 (putative)ENSG0000010404333
ATP8B1 / O43520 / ATPase phospholipid transporting 8B1ENSG0000008192333
ATP8B2 / P98198 / ATPase phospholipid transporting 8B2ENSG0000014351533
ATP10D / Q9P241 / ATPase phospholipid transporting 10D (putative)ENSG0000014524633
ATP10A / O60312 / ATPase phospholipid transporting 10A (putative)ENSG0000020619033
ATP8B3 / O60423 / ATPase phospholipid transporting 8B3ENSG0000013027029


Protein motifs (from Interpro)
Interpro ID Name
 IPR001757  P-type ATPase
 IPR006539  P-type ATPase, subfamily IV
 IPR008250  P-type ATPase, A domain superfamily
 IPR018303  P-type ATPase, phosphorylation site
 IPR023214  HAD superfamily
 IPR023298  P-type ATPase, transmembrane domain superfamily
 IPR023299  P-type ATPase, cytoplasmic domain N
 IPR030362  Probable phospholipid-transporting ATPase IF
 IPR032630  P-type ATPase, C-terminal
 IPR032631  P-type ATPase, N-terminal
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport NAS
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0015914 phospholipid transport IEA
 biological_processGO:0015917 aminophospholipid transport TAS
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045332 phospholipid translocation IEA
 cellular_componentGO:0005637 nuclear inner membrane NAS
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035577 azurophil granule membrane TAS
 cellular_componentGO:0055037 recycling endosome IDA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004012 phospholipid-translocating ATPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015075 ion transmembrane transporter activity NAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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