ENSG00000130270


Homo sapiens

Features
Gene ID: ENSG00000130270
  
Biological name :ATP8B3
  
Synonyms : ATP8B3 / ATPase phospholipid transporting 8B3 / O60423
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 1782075
Gene end: 1812276
  
Corresponding Affymetrix probe sets: 1554704_at (Human Genome U133 Plus 2.0 Array)   215319_at (Human Genome U133 Plus 2.0 Array)   239457_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000465027
Ensembl peptide - ENSP00000444334
Ensembl peptide - ENSP00000445204
Ensembl peptide - ENSP00000311336
Ensembl peptide - ENSP00000437115
Ensembl peptide - ENSP00000439993
NCBI entrez gene - 148229     See in Manteia.
OMIM - 605866
RefSeq - XM_011527711
RefSeq - XM_006722654
RefSeq - XM_006722655
RefSeq - XM_006722656
RefSeq - XM_011527707
RefSeq - XM_011527708
RefSeq - XM_011527709
RefSeq - XM_011527710
RefSeq - NM_001178002
RefSeq - NM_138813
RefSeq Peptide - NP_001171473
RefSeq Peptide - NP_620168
swissprot - K7EJ52
swissprot - F5H3R9
swissprot - F5GZM8
swissprot - O60423
swissprot - H0YFS1
Ensembl - ENSG00000130270
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atp8b3ENSDARG00000042285Danio rerio
 ATP8B3ENSGALG00000001084Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATP8B1 / O43520 / ATPase phospholipid transporting 8B1ENSG0000008192344
ATP8B2 / P98198 / ATPase phospholipid transporting 8B2ENSG0000014351540
ATP8B4 / Q8TF62 / ATPase phospholipid transporting 8B4 (putative)ENSG0000010404339
ATP8A2 / Q9NTI2 / ATPase phospholipid transporting 8A2ENSG0000013293232
ATP8A1 / Q9Y2Q0 / ATPase phospholipid transporting 8A1ENSG0000012440631
ATP10D / Q9P241 / ATPase phospholipid transporting 10D (putative)ENSG0000014524630
ATP10A / O60312 / ATPase phospholipid transporting 10A (putative)ENSG0000020619030
ATP11B / Q9Y2G3 / ATPase phospholipid transporting 11B (putative)ENSG0000005806326
ATP11A / P98196 / ATPase phospholipid transporting 11AENSG0000006865026
ATP11C / Q8NB49 / ATPase phospholipid transporting 11CENSG0000010197425


Protein motifs (from Interpro)
Interpro ID Name
 IPR001757  P-type ATPase
 IPR006539  P-type ATPase, subfamily IV
 IPR008250  P-type ATPase, A domain superfamily
 IPR018303  P-type ATPase, phosphorylation site
 IPR023214  HAD superfamily
 IPR023298  P-type ATPase, transmembrane domain superfamily
 IPR023299  P-type ATPase, cytoplasmic domain N
 IPR030349  Phospholipid-transporting ATPase IK
 IPR032630  P-type ATPase, C-terminal
 IPR032631  P-type ATPase, N-terminal
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0007030 Golgi organization IBA
 biological_processGO:0015914 phospholipid transport IEA
 biological_processGO:0045332 phospholipid translocation IEA
 cellular_componentGO:0002080 acrosomal membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004012 phospholipid-translocating ATPase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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