ENSG00000101974


Homo sapiens

Features
Gene ID: ENSG00000101974
  
Biological name :ATP11C
  
Synonyms : ATP11C / ATPase phospholipid transporting 11C / Q8NB49
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q27.1
Gene start: 139726346
Gene end: 139945276
  
Corresponding Affymetrix probe sets: 226785_at (Human Genome U133 Plus 2.0 Array)   242690_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391259
Ensembl peptide - ENSP00000359588
Ensembl peptide - ENSP00000394573
Ensembl peptide - ENSP00000397923
Ensembl peptide - ENSP00000332756
Ensembl peptide - ENSP00000355165
NCBI entrez gene - 286410     See in Manteia.
OMIM - 300516
RefSeq - XM_017029449
RefSeq - XM_017029442
RefSeq - XM_017029443
RefSeq - XM_017029444
RefSeq - XM_017029445
RefSeq - XM_017029446
RefSeq - XM_017029447
RefSeq - XM_017029448
RefSeq - NM_001010986
RefSeq - NM_173694
RefSeq - XM_017029439
RefSeq - XM_017029440
RefSeq - XM_017029441
RefSeq Peptide - NP_001010986
RefSeq Peptide - NP_775965
swissprot - H7C113
swissprot - A0A067XG57
swissprot - A0A067XG54
swissprot - Q8NB49
swissprot - H7C0E8
Ensembl - ENSG00000101974
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atp11cENSDARG00000036442Danio rerio
 ATP11CENSGALG00000006623Gallus gallus
 Atp11cENSMUSG00000062949Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATP11A / P98196 / ATPase phospholipid transporting 11AENSG0000006865063
ATP11B / Q9Y2G3 / ATPase phospholipid transporting 11B (putative)ENSG0000005806355
ATP8B2 / P98198 / ATPase phospholipid transporting 8B2ENSG0000014351533
ATP8B4 / Q8TF62 / ATPase phospholipid transporting 8B4 (putative)ENSG0000010404333
ATP8A1 / Q9Y2Q0 / ATPase phospholipid transporting 8A1ENSG0000012440633
ATP8A2 / Q9NTI2 / ATPase phospholipid transporting 8A2ENSG0000013293233
ATP8B1 / O43520 / ATPase phospholipid transporting 8B1ENSG0000008192332
ATP10A / O60312 / ATPase phospholipid transporting 10A (putative)ENSG0000020619032
ATP10D / Q9P241 / ATPase phospholipid transporting 10D (putative)ENSG0000014524632
ATP8B3 / O60423 / ATPase phospholipid transporting 8B3ENSG0000013027029


Protein motifs (from Interpro)
Interpro ID Name
 IPR001757  P-type ATPase
 IPR006539  P-type ATPase, subfamily IV
 IPR008250  P-type ATPase, A domain superfamily
 IPR018303  P-type ATPase, phosphorylation site
 IPR023214  HAD superfamily
 IPR023298  P-type ATPase, transmembrane domain superfamily
 IPR023299  P-type ATPase, cytoplasmic domain N
 IPR030363  Phospholipid-transporting ATPase IG
 IPR032630  P-type ATPase, C-terminal
 IPR032631  P-type ATPase, N-terminal
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002329 pre-B cell differentiation IEA
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0015914 phospholipid transport IEA
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0045332 phospholipid translocation IEA
 biological_processGO:0045579 positive regulation of B cell differentiation IEA
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0055037 recycling endosome IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004012 phospholipid-translocating ATPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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