ENSG00000104043


Homo sapiens

Features
Gene ID: ENSG00000104043
  
Biological name :ATP8B4
  
Synonyms : ATP8B4 / ATPase phospholipid transporting 8B4 (putative) / Q8TF62
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q21.2
Gene start: 49858238
Gene end: 50182817
  
Corresponding Affymetrix probe sets: 220416_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453690
Ensembl peptide - ENSP00000453482
Ensembl peptide - ENSP00000453539
Ensembl peptide - ENSP00000284509
Ensembl peptide - ENSP00000452956
Ensembl peptide - ENSP00000453143
Ensembl peptide - ENSP00000453169
Ensembl peptide - ENSP00000453229
NCBI entrez gene - 79895     See in Manteia.
OMIM - 609123
RefSeq - XM_017022599
RefSeq - XM_017022592
RefSeq - XM_017022593
RefSeq - XM_017022594
RefSeq - XM_017022595
RefSeq - XM_017022596
RefSeq - XM_017022597
RefSeq - XM_017022598
RefSeq - NM_024837
RefSeq - XM_011522046
RefSeq - XM_011522047
RefSeq - XM_011522048
RefSeq - XM_011522049
RefSeq - XM_011522051
RefSeq - XM_011522052
RefSeq - XM_011522053
RefSeq - XM_011522056
RefSeq - XM_011522058
RefSeq - XM_011522059
RefSeq - XM_011522060
RefSeq - XM_011522061
RefSeq - XM_011522062
RefSeq - XM_011522063
RefSeq - XM_011522064
RefSeq - XM_011522069
RefSeq - XM_017022587
RefSeq - XM_017022588
RefSeq - XM_017022589
RefSeq - XM_017022590
RefSeq - XM_017022591
RefSeq Peptide - NP_079113
swissprot - H0YM66
swissprot - H0YMB5
swissprot - H0YLJ1
swissprot - H0YLC1
swissprot - Q8TF62
swissprot - H0YMP8
Ensembl - ENSG00000104043
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atp8b4ENSDARG00000079453Danio rerio
 Atp8b4ENSMUSG00000060131Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATP8B2 / P98198 / ATPase phospholipid transporting 8B2ENSG0000014351571
ATP8B1 / O43520 / ATPase phospholipid transporting 8B1ENSG0000008192354
ATP8B3 / O60423 / ATPase phospholipid transporting 8B3ENSG0000013027042
ATP8A2 / Q9NTI2 / ATPase phospholipid transporting 8A2ENSG0000013293239
ATP8A1 / Q9Y2Q0 / ATPase phospholipid transporting 8A1ENSG0000012440638
ATP10A / O60312 / ATPase phospholipid transporting 10A (putative)ENSG0000020619035
ATP10D / Q9P241 / ATPase phospholipid transporting 10D (putative)ENSG0000014524635
ATP11B / Q9Y2G3 / ATPase phospholipid transporting 11B (putative)ENSG0000005806332
ATP11A / P98196 / ATPase phospholipid transporting 11AENSG0000006865032
ATP11C / Q8NB49 / ATPase phospholipid transporting 11CENSG0000010197432


Protein motifs (from Interpro)
Interpro ID Name
 IPR001757  P-type ATPase
 IPR006539  P-type ATPase, subfamily IV
 IPR008250  P-type ATPase, A domain superfamily
 IPR018303  P-type ATPase, phosphorylation site
 IPR023298  P-type ATPase, transmembrane domain superfamily
 IPR023299  P-type ATPase, cytoplasmic domain N
 IPR030348  Probable phospholipid-transporting ATPase IM
 IPR032630  P-type ATPase, C-terminal
 IPR032631  P-type ATPase, N-terminal
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0007030 Golgi organization IBA
 biological_processGO:0015914 phospholipid transport IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045332 phospholipid translocation IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0070821 tertiary granule membrane TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004012 phospholipid-translocating ATPase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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