ENSG00000072571


Homo sapiens

Features
Gene ID: ENSG00000072571
  
Biological name :HMMR
  
Synonyms : HMMR / hyaluronan mediated motility receptor / O75330
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q34
Gene start: 163460203
Gene end: 163491945
  
Corresponding Affymetrix probe sets: 207165_at (Human Genome U133 Plus 2.0 Array)   209709_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000377492
Ensembl peptide - ENSP00000428481
Ensembl peptide - ENSP00000428406
Ensembl peptide - ENSP00000402673
Ensembl peptide - ENSP00000185942
Ensembl peptide - ENSP00000351554
NCBI entrez gene - 3161     See in Manteia.
OMIM - 600936
RefSeq - NM_012484
RefSeq - NM_012485
RefSeq - NM_001142556
RefSeq - NM_001142557
RefSeq Peptide - NP_001136029
RefSeq Peptide - NP_036617
RefSeq Peptide - NP_001136028
RefSeq Peptide - NP_036616
swissprot - O75330
swissprot - E5RI30
swissprot - E5RIH2
Ensembl - ENSG00000072571
  
Related genetic diseases (OMIM): 114480 - {Breast cancer, susceptibility to}, 114480
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hmmrENSDARG00000021794Danio rerio
 HMMRENSGALG00000042009Gallus gallus
 HmmrENSMUSG00000020330Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026203  Intracellular hyaluronic acid binding protein
 IPR031787  Hyaluronan mediated motility receptor, N-terminal
 IPR031794  Hyaluronan-mediated motility receptor, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010389 regulation of G2/M transition of mitotic cell cycle TAS
 biological_processGO:0030214 hyaluronan catabolic process TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005540 hyaluronic acid binding IEA


Pathways (from Reactome)
Pathway description
Hyaluronan uptake and degradation
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000090020 P19634 / SLC9A1 / solute carrier family 9 member A1  / complex / reaction
 ENSG00000088325 TPX2 / Q9ULW0 / TPX2, microtubule nucleation factor  / complex / reaction
 ENSG00000087586 AURKA / O14965 / aurora kinase A  / complex / reaction
 ENSG00000187446 CHP1 / Q99653 / calcineurin like EF-hand protein 1  / reaction / complex
 ENSG00000068001 HYAL2 / Q12891 / hyaluronoglucosaminidase 2  / complex / reaction






 

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