ENSG00000076344


Homo sapiens

Features
Gene ID: ENSG00000076344
  
Biological name :RGS11
  
Synonyms : O94810 / regulator of G protein signaling 11 / RGS11
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p13.3
Gene start: 268301
Gene end: 275980
  
Corresponding Affymetrix probe sets: 1554643_at (Human Genome U133 Plus 2.0 Array)   206107_at (Human Genome U133 Plus 2.0 Array)   211872_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000168869
Ensembl peptide - ENSP00000319069
Ensembl peptide - ENSP00000352778
Ensembl peptide - ENSP00000380876
NCBI entrez gene - 8786     See in Manteia.
OMIM - 603895
RefSeq - XM_011522720
RefSeq - NM_001286485
RefSeq - NM_001286486
RefSeq - NM_003834
RefSeq - NM_183337
RefSeq - XM_011522719
RefSeq Peptide - NP_003825
RefSeq Peptide - NP_899180
RefSeq Peptide - NP_001273414
RefSeq Peptide - NP_001273415
swissprot - O94810
swissprot - Q4TT70
swissprot - H7C5Z0
Ensembl - ENSG00000076344
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rgs11ENSDARG00000037646Danio rerio
 RGS11ENSGALG00000040648Gallus gallus
 Rgs11ENSMUSG00000024186Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RGS9 / O75916 / regulator of G protein signaling 9ENSG0000010837051
RGS7 / P49802 / regulator of G protein signaling 7ENSG0000018290136
RGS6 / P49758 / regulator of G protein signaling 6ENSG0000018273234
RGS12 / O14924 / regulator of G protein signaling 12ENSG0000015978827
RGS14 / O43566 / regulator of G protein signaling 14ENSG0000016922015
RGS10 / O43665 / regulator of G protein signaling 10ENSG0000014890811


Protein motifs (from Interpro)
Interpro ID Name
 IPR000591  DEP domain
 IPR015898  G-protein gamma-like domain
 IPR016137  RGS domain
 IPR024066  RGS, subdomain 1/3
 IPR036284  G-protein gamma-like domain superfamily
 IPR036305  RGS domain superfamily
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway TAS
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005834 heterotrimeric G-protein complex IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0031681 G-protein beta-subunit binding IPI


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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