ENSG00000182732


Homo sapiens

Features
Gene ID: ENSG00000182732
  
Biological name :RGS6
  
Synonyms : P49758 / regulator of G protein signaling 6 / RGS6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q24.2
Gene start: 71932439
Gene end: 72566529
  
Corresponding Affymetrix probe sets: 210270_at (Human Genome U133 Plus 2.0 Array)   211448_s_at (Human Genome U133 Plus 2.0 Array)   214538_x_at (Human Genome U133 Plus 2.0 Array)   236726_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000451855
Ensembl peptide - ENSP00000451030
Ensembl peptide - ENSP00000451912
Ensembl peptide - ENSP00000496764
Ensembl peptide - ENSP00000478186
Ensembl peptide - ENSP00000452331
Ensembl peptide - ENSP00000341199
Ensembl peptide - ENSP00000347699
Ensembl peptide - ENSP00000383953
Ensembl peptide - ENSP00000384218
Ensembl peptide - ENSP00000384612
Ensembl peptide - ENSP00000385243
Ensembl peptide - ENSP00000412144
Ensembl peptide - ENSP00000450858
Ensembl peptide - ENSP00000450936
NCBI entrez gene - 9628     See in Manteia.
OMIM - 603894
RefSeq - XM_017021834
RefSeq - XM_017021818
RefSeq - XM_017021819
RefSeq - XM_017021820
RefSeq - XM_017021821
RefSeq - XM_017021822
RefSeq - XM_017021823
RefSeq - XM_017021824
RefSeq - XM_017021825
RefSeq - XM_017021826
RefSeq - XM_017021827
RefSeq - XM_017021828
RefSeq - XM_017021829
RefSeq - XM_017021830
RefSeq - XM_017021831
RefSeq - XM_017021832
RefSeq - XM_017021833
RefSeq - NM_001204416
RefSeq - NM_001204417
RefSeq - NM_001204418
RefSeq - NM_001204419
RefSeq - NM_001204420
RefSeq - NM_001204421
RefSeq - NM_001204422
RefSeq - NM_001204423
RefSeq - NM_001204424
RefSeq - NM_004296
RefSeq - XM_011537393
RefSeq - XM_011537397
RefSeq - XM_011537407
RefSeq Peptide - NP_001191347
RefSeq Peptide - NP_001191351
RefSeq Peptide - NP_001191352
RefSeq Peptide - NP_001191353
RefSeq Peptide - NP_004287
RefSeq Peptide - NP_001191345
RefSeq Peptide - NP_001191346
RefSeq Peptide - NP_001191348
RefSeq Peptide - NP_001191349
RefSeq Peptide - NP_001191350
swissprot - B7Z2N1
swissprot - A0A0A0MRA9
swissprot - Q2M3K2
swissprot - A0A087WTW9
swissprot - B7Z7N5
swissprot - P49758
Ensembl - ENSG00000182732
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rgs6ENSDARG00000015627Danio rerio
 RGS6ENSGALG00000009368Gallus gallus
 Rgs6ENSMUSG00000021219Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RGS7 / P49802 / regulator of G protein signaling 7ENSG0000018290172
RGS9 / O75916 / regulator of G protein signaling 9ENSG0000010837036
RGS11 / O94810 / regulator of G protein signaling 11ENSG0000007634433
RGS12 / O14924 / regulator of G protein signaling 12ENSG0000015978823
RGS14 / O43566 / regulator of G protein signaling 14ENSG0000016922012
RGS10 / O43665 / regulator of G protein signaling 10ENSG000001489089


Protein motifs (from Interpro)
Interpro ID Name
 IPR000591  DEP domain
 IPR015898  G-protein gamma-like domain
 IPR016137  RGS domain
 IPR024066  RGS, subdomain 1/3
 IPR036284  G-protein gamma-like domain superfamily
 IPR036305  RGS domain superfamily
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway TAS
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005834 heterotrimeric G-protein complex IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IDA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr