ENSG00000182901


Homo sapiens

Features
Gene ID: ENSG00000182901
  
Biological name :RGS7
  
Synonyms : P49802 / regulator of G protein signaling 7 / RGS7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q43
Gene start: 240775515
Gene end: 241357230
  
Corresponding Affymetrix probe sets: 1554500_a_at (Human Genome U133 Plus 2.0 Array)   206290_s_at (Human Genome U133 Plus 2.0 Array)   216970_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355522
Ensembl peptide - ENSP00000341242
Ensembl peptide - ENSP00000355521
Ensembl peptide - ENSP00000355523
Ensembl peptide - ENSP00000404399
NCBI entrez gene - 6000     See in Manteia.
OMIM - 602517
RefSeq - XM_017002013
RefSeq - NM_001282773
RefSeq - NM_001282775
RefSeq - NM_001282778
RefSeq - NM_002924
RefSeq - XM_017002007
RefSeq - XM_017002008
RefSeq - XM_017002009
RefSeq - XM_017002010
RefSeq - XM_017002011
RefSeq - XM_017002012
RefSeq - XM_005273218
RefSeq - XM_006711800
RefSeq - XM_011544246
RefSeq - XM_011544247
RefSeq - XM_017002001
RefSeq - XM_017002002
RefSeq - XM_017002003
RefSeq - XM_017002004
RefSeq - XM_017002005
RefSeq - XM_017002006
RefSeq Peptide - NP_001269704
RefSeq Peptide - NP_001269707
RefSeq Peptide - NP_002915
RefSeq Peptide - NP_001269702
swissprot - P49802
swissprot - Q5T3H5
Ensembl - ENSG00000182901
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rgs7aENSDARG00000016584Danio rerio
 rgs7bENSDARG00000096687Danio rerio
 RGS7ENSGALG00000039772Gallus gallus
 Rgs7ENSMUSG00000026527Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RGS6 / P49758 / regulator of G protein signaling 6ENSG0000018273272
RGS9 / O75916 / regulator of G protein signaling 9ENSG0000010837035
RGS11 / O94810 / regulator of G protein signaling 11ENSG0000007634435
RGS12 / O14924 / regulator of G protein signaling 12ENSG0000015978824
RGS14 / O43566 / regulator of G protein signaling 14ENSG0000016922012
RGS10 / O43665 / regulator of G protein signaling 10ENSG0000014890810


Protein motifs (from Interpro)
Interpro ID Name
 IPR000591  DEP domain
 IPR015898  G-protein gamma-like domain
 IPR016137  RGS domain
 IPR024066  RGS, subdomain 1/3
 IPR036284  G-protein gamma-like domain superfamily
 IPR036305  RGS domain superfamily
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005834 heterotrimeric G-protein complex IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0031681 G-protein beta-subunit binding IPI


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000069966 GNB5 / O14775 / G protein subunit beta 5  / reaction / complex






 

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