ENSG00000086570


Homo sapiens

Features
Gene ID: ENSG00000086570
  
Biological name :FAT2
  
Synonyms : FAT2 / FAT atypical cadherin 2 / Q9NYQ8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q33.1
Gene start: 151504093
Gene end: 151568944
  
Corresponding Affymetrix probe sets: 208153_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000261800
Ensembl peptide - ENSP00000429678
NCBI entrez gene - 2196     See in Manteia.
OMIM - 604269
RefSeq - XM_017009225
RefSeq - NM_001447
RefSeq - XM_011537600
RefSeq - XM_011537603
RefSeq - XM_017009224
RefSeq - XM_006714761
RefSeq Peptide - NP_001438
swissprot - Q9NYQ8
swissprot - H0YBK2
Ensembl - ENSG00000086570
  
Related genetic diseases (OMIM): 617769 - Spinocerebellar ataxia 45, 617769
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fat2ENSDARG00000018923Danio rerio
 FAT2ENSGALG00000004320Gallus gallus
 Fat2ENSMUSG00000055333Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FAT1 / Q14517 / FAT atypical cadherin 1ENSG0000008385744
FAT3 / Q8TDW7 / FAT atypical cadherin 3ENSG0000016532341
FAT4 / Q6V0I7 / FAT atypical cadherin 4ENSG0000019615923
DCHS1 / Q96JQ0 / dachsous cadherin-related 1ENSG0000016634120
CELSR1 / Q9NYQ6 / cadherin EGF LAG seven-pass G-type receptor 1ENSG0000007527513
CELSR3 / Q9NYQ7 / cadherin EGF LAG seven-pass G-type receptor 3ENSG0000000830013
CELSR2 / Q9HCU4 / cadherin EGF LAG seven-pass G-type receptor 2ENSG0000014312613
CDH23 / Q9H251 / cadherin related 23ENSG000001077369


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR002126  Cadherin
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules ISS
 biological_processGO:0010631 epithelial cell migration IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005913 cell-cell adherens junction IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr