ENSG00000083857


Homo sapiens

Features
Gene ID: ENSG00000083857
  
Biological name :FAT1
  
Synonyms : FAT1 / FAT atypical cadherin 1 / Q14517
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q35.2
Gene start: 186587783
Gene end: 186726722
  
Corresponding Affymetrix probe sets: 201579_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000421003
Ensembl peptide - ENSP00000479573
Ensembl peptide - ENSP00000424157
Ensembl peptide - ENSP00000423801
Ensembl peptide - ENSP00000423736
Ensembl peptide - ENSP00000406229
Ensembl peptide - ENSP00000420869
NCBI entrez gene - 2195     See in Manteia.
OMIM - 600976
RefSeq - NM_005245
RefSeq - XM_005262834
RefSeq - XM_005262835
RefSeq - XM_006714139
RefSeq Peptide - NP_005236
swissprot - Q14517
swissprot - H0Y9H4
swissprot - D6RCE4
swissprot - A0A087WVP1
swissprot - H0Y8F5
swissprot - H0Y9C8
swissprot - D6RHE6
Ensembl - ENSG00000083857
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fat1aENSDARG00000017591Danio rerio
 fat1bENSDARG00000019063Danio rerio
 FAT1ENSGALG00000013579Gallus gallus
 Fat1ENSMUSG00000070047Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FAT3 / Q8TDW7 / FAT atypical cadherin 3ENSG0000016532350
FAT2 / Q9NYQ8 / FAT atypical cadherin 2ENSG0000008657042
FAT4 / Q6V0I7 / FAT atypical cadherin 4ENSG0000019615924
DCHS1 / Q96JQ0 / dachsous cadherin-related 1ENSG0000016634119
CELSR2 / Q9HCU4 / cadherin EGF LAG seven-pass G-type receptor 2ENSG0000014312613
CELSR3 / Q9NYQ7 / cadherin EGF LAG seven-pass G-type receptor 3ENSG0000000830013
CELSR1 / Q9NYQ6 / cadherin EGF LAG seven-pass G-type receptor 1ENSG0000007527513
CDH23 / Q9H251 / cadherin related 23ENSG000001077368


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR002126  Cadherin
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR015919  Cadherin-like
 IPR018097  EGF-like calcium-binding, conserved site
 IPR020894  Cadherin conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0007163 establishment or maintenance of cell polarity IEA
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0009653 anatomical structure morphogenesis TAS
 biological_processGO:0016477 cell migration ISS
 biological_processGO:0098609 cell-cell adhesion IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr