ENSG00000087303


Homo sapiens

Features
Gene ID: ENSG00000087303
  
Biological name :NID2
  
Synonyms : NID2 / nidogen 2 / Q14112
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q22.1
Gene start: 52004803
Gene end: 52069228
  
Corresponding Affymetrix probe sets: 204114_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000482803
Ensembl peptide - ENSP00000216286
Ensembl peptide - ENSP00000452190
NCBI entrez gene - 22795     See in Manteia.
OMIM - 605399
RefSeq - XM_005267407
RefSeq - NM_007361
RefSeq - XM_005267405
RefSeq - XM_005267406
RefSeq Peptide - NP_031387
swissprot - Q14112
swissprot - H0YJV3
swissprot - A0A087WZP6
Ensembl - ENSG00000087303
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nid2aENSDARG00000075707Danio rerio
 nid2bENSDARG00000009471Danio rerio
 NID2ENSGALG00000012394Gallus gallus
 Nid2ENSMUSG00000021806Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NID1 / P14543 / nidogen 1ENSG0000011696239
EGF / P01133 / epidermal growth factorENSG0000013879814
LRP5L / A4QPB2 / LDL receptor related protein 5 likeENSG000001000685


Protein motifs (from Interpro)
Interpro ID Name
 IPR000033  LDLR class B repeat
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000716  Thyroglobulin type-1
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR003886  NIDO domain
 IPR006605  G2 nidogen/fibulin G2F
 IPR009017  Green fluorescent protein
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR024731  EGF domain
 IPR026823  Complement Clr-like EGF domain
 IPR036857  Thyroglobulin type-1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0071711 basement membrane organization TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005604 basement membrane TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0031012 extracellular matrix ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005518 collagen binding TAS


Pathways (from Reactome)
Pathway description
Laminin interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000142798 HSPG2 / P98160 / heparan sulfate proteoglycan 2  / reaction / complex






 

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