ENSG00000092199


Homo sapiens

Features
Gene ID: ENSG00000092199
  
Biological name :HNRNPC
  
Synonyms : heterogeneous nuclear ribonucleoprotein C (C1/C2) / HNRNPC / P07910
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q11.2
Gene start: 21209136
Gene end: 21269494
  
Corresponding Affymetrix probe sets: 1568941_a_at (Human Genome U133 Plus 2.0 Array)   200014_s_at (Human Genome U133 Plus 2.0 Array)   200751_s_at (Human Genome U133 Plus 2.0 Array)   212626_x_at (Human Genome U133 Plus 2.0 Array)   214737_x_at (Human Genome U133 Plus 2.0 Array)   227110_at (Human Genome U133 Plus 2.0 Array)   235500_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000450669
Ensembl peptide - ENSP00000338095
Ensembl peptide - ENSP00000404559
Ensembl peptide - ENSP00000404848
Ensembl peptide - ENSP00000442816
Ensembl peptide - ENSP00000450467
Ensembl peptide - ENSP00000450544
Ensembl peptide - ENSP00000450548
Ensembl peptide - ENSP00000450601
Ensembl peptide - ENSP00000450629
Ensembl peptide - ENSP00000450725
Ensembl peptide - ENSP00000450790
Ensembl peptide - ENSP00000451176
Ensembl peptide - ENSP00000451187
Ensembl peptide - ENSP00000451291
Ensembl peptide - ENSP00000451292
Ensembl peptide - ENSP00000451652
Ensembl peptide - ENSP00000451708
Ensembl peptide - ENSP00000451892
Ensembl peptide - ENSP00000452021
Ensembl peptide - ENSP00000452185
Ensembl peptide - ENSP00000452213
Ensembl peptide - ENSP00000452214
Ensembl peptide - ENSP00000452276
Ensembl peptide - ENSP00000452545
Ensembl peptide - ENSP00000452573
Ensembl peptide - ENSP00000452599
NCBI entrez gene - 3183     See in Manteia.
OMIM - 164020
RefSeq - XM_011536712
RefSeq - XM_017021252
RefSeq - XM_017021253
RefSeq - XM_011536710
RefSeq - XM_011536711
RefSeq - NM_001077442
RefSeq - NM_001077443
RefSeq - NM_004500
RefSeq - NM_031314
RefSeq - XM_006720125
RefSeq - XM_011536708
RefSeq - XM_011536709
RefSeq Peptide - NP_001070910
RefSeq Peptide - NP_004491
RefSeq Peptide - NP_112604
RefSeq Peptide - NP_001070911
swissprot - G3V575
swissprot - G3V576
swissprot - G3V5V7
swissprot - G3V5X6
swissprot - G3V251
swissprot - P07910
swissprot - G3V2H6
swissprot - G3V2Q1
swissprot - G3V2D6
swissprot - B2R5W2
swissprot - B4DSU6
swissprot - B4DY08
swissprot - G3V4C1
swissprot - G3V3K6
swissprot - G3V4M8
swissprot - G3V4W0
swissprot - G3V555
Ensembl - ENSG00000092199
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hnrnpcENSDARG00000053810Danio rerio
 zgc:55733ENSDARG00000103845Danio rerio
 HnrnpcENSMUSG00000060373Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O60812 / HNRNPCL1 / heterogeneous nuclear ribonucleoprotein C-like 1ENSG0000017917287
B2RXH8 / HNRNPCL2 / heterogeneous nuclear ribonucleoprotein C-like 2ENSG0000027577485
B7ZW38 / HNRNPCL3 / heterogeneous nuclear ribonucleoprotein C-like 3ENSG0000027705885
P0DMR1 / HNRNPCL4 / heterogeneous nuclear ribonucleoprotein C-like 4ENSG0000017941285
RALYL / Q86SE5 / RALY RNA binding protein likeENSG0000018467248
RALY / Q9UKM9 / RALY heterogeneous nuclear ribonucleoproteinENSG0000012597047


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR017347  Heterogeneous nuclear ribonucleoprotein C
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0001649 osteoblast differentiation HDA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing TAS
 biological_processGO:0016070 RNA metabolic process TAS
 biological_processGO:0032211 negative regulation of telomere maintenance via telomerase IMP
 biological_processGO:0043044 ATP-dependent chromatin remodeling HDA
 biological_processGO:0070935 3"-UTR-mediated mRNA stabilization IMP
 cellular_componentGO:0000790 nuclear chromatin HDA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005681 spliceosomal complex IDA
 cellular_componentGO:0005697 telomerase holoenzyme complex IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0045120 pronucleus IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding HDA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding HDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008266 poly(U) RNA binding IDA
 molecular_functionGO:0031492 nucleosomal DNA binding HDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0070034 telomerase RNA binding IPI
 molecular_functionGO:1990247 N6-methyladenosine-containing RNA binding IDA


Pathways (from Reactome)
Pathway description
SUMOylation of RNA binding proteins
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000116030 SUMO1 / P63165 / small ubiquitin-like modifier 1  / complex / reaction
 ENSG00000103275 UBE2I / P63279 / ubiquitin conjugating enzyme E2 I  / reaction






 

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