ENSG00000095066


Homo sapiens

Features
Gene ID: ENSG00000095066
  
Biological name :HOOK2
  
Synonyms : HOOK2 / hook microtubule tethering protein 2 / Q96ED9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.13
Gene start: 12763003
Gene end: 12872740
  
Corresponding Affymetrix probe sets: 218780_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467097
Ensembl peptide - ENSP00000466497
Ensembl peptide - ENSP00000466616
Ensembl peptide - ENSP00000264827
Ensembl peptide - ENSP00000380785
Ensembl peptide - ENSP00000465023
Ensembl peptide - ENSP00000465042
Ensembl peptide - ENSP00000465091
Ensembl peptide - ENSP00000465427
NCBI entrez gene - 29911     See in Manteia.
OMIM - 607824
RefSeq - XM_017026721
RefSeq - XM_005259873
RefSeq - XM_005259874
RefSeq - XM_005259876
RefSeq - XM_005259877
RefSeq - XM_011527943
RefSeq - XM_011527944
RefSeq - XM_011527945
RefSeq - XM_011527946
RefSeq - XM_011527947
RefSeq - XM_017026720
RefSeq - NM_001100176
RefSeq - NM_013312
RefSeq Peptide - NP_001093646
RefSeq Peptide - NP_037444
swissprot - K7EK29
swissprot - K7EMG7
swissprot - K7EMR5
swissprot - K7EJ65
swissprot - Q96ED9
swissprot - K7EJ48
swissprot - K7ENU5
swissprot - K7EJA7
Ensembl - ENSG00000095066
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hook2ENSDARG00000039309Danio rerio
 hook2ENSDARG00000099235Danio rerio
 2 ENSMUSG00000052566Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOOK3 / Q86VS8 / hook microtubule tethering protein 3ENSG0000016817250
HOOK1 / Q9UJC3 / hook microtubule tethering protein 1ENSG0000013470948
Q9P219 / CCDC88C / coiled-coil domain containing 88CENSG0000001513325
A6NC98 / CCDC88B / coiled-coil domain containing 88BENSG0000016807124
Q3V6T2 / CCDC88A / coiled-coil domain containing 88AENSG0000011535523


Protein motifs (from Interpro)
Interpro ID Name
 IPR008636  Hook-like protein family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis TAS
 biological_processGO:0007032 endosome organization IMP
 biological_processGO:0007040 lysosome organization IMP
 biological_processGO:0008333 endosome to lysosome transport IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0030705 cytoskeleton-dependent intracellular transport IBA
 biological_processGO:0031122 cytoplasmic microtubule organization IBA
 biological_processGO:0045022 early endosome to late endosome transport IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0030897 HOPS complex IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070695 FHF complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IBA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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