ENSG00000168172


Homo sapiens

Features
Gene ID: ENSG00000168172
  
Biological name :HOOK3
  
Synonyms : HOOK3 / hook microtubule tethering protein 3 / Q86VS8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p11.21
Gene start: 42896932
Gene end: 43030539
  
Corresponding Affymetrix probe sets: 1558315_s_at (Human Genome U133 Plus 2.0 Array)   224359_s_at (Human Genome U133 Plus 2.0 Array)   226395_at (Human Genome U133 Plus 2.0 Array)   235114_x_at (Human Genome U133 Plus 2.0 Array)   236192_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000305699
Ensembl peptide - ENSP00000433953
Ensembl peptide - ENSP00000435077
Ensembl peptide - ENSP00000433813
NCBI entrez gene - 84376     See in Manteia.
OMIM - 607825
RefSeq - NM_032410
RefSeq Peptide - NP_115786
swissprot - Q86VS8
swissprot - H0YDK4
swissprot - H0YDM4
swissprot - H0YE69
Ensembl - ENSG00000168172
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HOOK3ENSDARG00000114329Danio rerio
 HOOK3ENSGALG00000015390Gallus gallus
 3 ENSMUSG00000037234Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOOK1 / Q9UJC3 / hook microtubule tethering protein 1ENSG0000013470959
HOOK2 / Q96ED9 / hook microtubule tethering protein 2ENSG0000009506650
Q3V6T2 / CCDC88A / coiled-coil domain containing 88AENSG0000011535526
Q9P219 / CCDC88C / coiled-coil domain containing 88CENSG0000001513325
A6NC98 / CCDC88B / coiled-coil domain containing 88BENSG0000016807123


Protein motifs (from Interpro)
Interpro ID Name
 IPR008636  Hook-like protein family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007032 endosome organization IMP
 biological_processGO:0007040 lysosome organization IMP
 biological_processGO:0008333 endosome to lysosome transport IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0022027 interkinetic nuclear migration IEA
 biological_processGO:0030705 cytoskeleton-dependent intracellular transport IBA
 biological_processGO:0031122 cytoplasmic microtubule organization IMP
 biological_processGO:0034454 microtubule anchoring at centrosome IEA
 biological_processGO:0045022 early endosome to late endosome transport IMP
 biological_processGO:0050768 negative regulation of neurogenesis IEA
 biological_processGO:0051645 Golgi localization IMP
 biological_processGO:0071539 protein localization to centrosome IEA
 biological_processGO:0097150 neuronal stem cell population maintenance IEA
 cellular_componentGO:0000242 pericentriolar material IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005801 cis-Golgi network IDA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0030897 HOPS complex IDA
 cellular_componentGO:0034451 centriolar satellite IEA
 cellular_componentGO:0070695 FHF complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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