ENSG00000134709


Homo sapiens

Features
Gene ID: ENSG00000134709
  
Biological name :HOOK1
  
Synonyms : HOOK1 / hook microtubule tethering protein 1 / Q9UJC3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p32.1
Gene start: 59814786
Gene end: 59876378
  
Corresponding Affymetrix probe sets: 219976_at (Human Genome U133 Plus 2.0 Array)   225792_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000398860
Ensembl peptide - ENSP00000360252
NCBI entrez gene - 51361     See in Manteia.
OMIM - 607820
RefSeq - XM_011541563
RefSeq - NM_015888
RefSeq - XM_006710676
RefSeq - XM_011541562
RefSeq Peptide - NP_056972
swissprot - B1AK95
swissprot - Q9UJC3
Ensembl - ENSG00000134709
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hook1ENSDARG00000042946Danio rerio
 HOOK1ENSGALG00000010889Gallus gallus
 1 ENSMUSG00000028572Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HOOK3 / Q86VS8 / hook microtubule tethering protein 3ENSG0000016817258
HOOK2 / Q96ED9 / hook microtubule tethering protein 2ENSG0000009506647
Q3V6T2 / CCDC88A / coiled-coil domain containing 88AENSG0000011535524
Q9P219 / CCDC88C / coiled-coil domain containing 88CENSG0000001513323
A6NC98 / CCDC88B / coiled-coil domain containing 88BENSG0000016807121


Protein motifs (from Interpro)
Interpro ID Name
 IPR008636  Hook-like protein family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007032 endosome organization IMP
 biological_processGO:0007040 lysosome organization IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007286 spermatid development IEA
 biological_processGO:0008333 endosome to lysosome transport IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030705 cytoskeleton-dependent intracellular transport IBA
 biological_processGO:0031122 cytoplasmic microtubule organization IBA
 biological_processGO:0045022 early endosome to late endosome transport IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0030897 HOPS complex IDA
 cellular_componentGO:0070695 FHF complex IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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