ENSG00000099194


Homo sapiens

Features
Gene ID: ENSG00000099194
  
Biological name :SCD
  
Synonyms : O00767 / SCD / stearoyl-CoA desaturase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q24.31
Gene start: 100347124
Gene end: 100364834
  
Corresponding Affymetrix probe sets: 200831_s_at (Human Genome U133 Plus 2.0 Array)   200832_s_at (Human Genome U133 Plus 2.0 Array)   211162_x_at (Human Genome U133 Plus 2.0 Array)   211708_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359380
NCBI entrez gene - 6319     See in Manteia.
OMIM - 604031
RefSeq - NM_005063
RefSeq Peptide - NP_005054
swissprot - O00767
Ensembl - ENSG00000099194
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scdENSDARG00000033662Danio rerio
 scdbENSDARG00000030265Danio rerio
 SCDENSGALG00000005739Gallus gallus
 Scd1ENSMUSG00000037071Mus musculus
 Scd2ENSMUSG00000025203Mus musculus
 Scd3ENSMUSG00000025202Mus musculus
 Scd4ENSMUSG00000050195Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SCD5 / Q86SK9 / stearoyl-CoA desaturase 5ENSG0000014528453


Protein motifs (from Interpro)
Interpro ID Name
 IPR001522  Fatty acid desaturase type 1, conserved site
 IPR015876  Acyl-CoA desaturase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0006636 unsaturated fatty acid biosynthetic process IDA
 biological_processGO:0045540 regulation of cholesterol biosynthetic process TAS
 biological_processGO:0046949 fatty-acyl-CoA biosynthetic process TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1903966 monounsaturated fatty acid biosynthetic process IBA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004768 stearoyl-CoA 9-desaturase activity TAS
 molecular_functionGO:0005506 iron ion binding IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Activation of gene expression by SREBF (SREBP)
Fatty acyl-CoA biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000099194 SCD / O00767 / stearoyl-CoA desaturase  / complex






 

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