ENSG00000099364


Homo sapiens

Features
Gene ID: ENSG00000099364
  
Biological name :FBXL19
  
Synonyms : F-box and leucine rich repeat protein 19 / FBXL19 / Q6PCT2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p11.2
Gene start: 30923055
Gene end: 30948783
  
Corresponding Affymetrix probe sets: 228277_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454344
Ensembl peptide - ENSP00000455337
Ensembl peptide - ENSP00000455529
Ensembl peptide - ENSP00000455871
Ensembl peptide - ENSP00000457199
Ensembl peptide - ENSP00000458033
Ensembl peptide - ENSP00000339712
Ensembl peptide - ENSP00000369666
Ensembl peptide - ENSP00000397913
NCBI entrez gene - 54620     See in Manteia.
OMIM - 609085
RefSeq - NM_001099784
RefSeq - NM_001282351
RefSeq Peptide - NP_001093254
RefSeq Peptide - NP_001269280
swissprot - Q6PCT2
swissprot - H3BME1
swissprot - H3BPI8
swissprot - H3BPZ0
swissprot - H3BQP6
swissprot - H3BTJ3
swissprot - H3BVB1
swissprot - H7C112
Ensembl - ENSG00000099364
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 btr30ENSDARG00000103362Danio rerio
 Fbxl19ENSMUSG00000030811Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KDM2B / Q8NHM5 / lysine demethylase 2BENSG0000008909446
KDM2A / Q9Y2K7 / lysine demethylase 2AENSG0000017312034
PHF2 / O75151 / PHD finger protein 2ENSG0000019772411
PHF8 / Q9UPP1 / PHD finger protein 8ENSG0000017294310
KDM7A / Q6ZMT4 / lysine demethylase 7AENSG000000064597


Protein motifs (from Interpro)
Interpro ID Name
 IPR001810  F-box domain
 IPR001965  Zinc finger, PHD-type
 IPR002857  Zinc finger, CXXC-type
 IPR006553  Leucine-rich repeat, cysteine-containing subtype
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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