ENSG00000099617


Homo sapiens

Features
Gene ID: ENSG00000099617
  
Biological name :EFNA2
  
Synonyms : EFNA2 / ephrin A2 / O43921
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.3
Gene start: 1286154
Gene end: 1300237
  
Corresponding Affymetrix probe sets: 1553573_s_at (Human Genome U133 Plus 2.0 Array)   208256_at (Human Genome U133 Plus 2.0 Array)   238956_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000215368
NCBI entrez gene - 1943     See in Manteia.
OMIM - 602756
RefSeq - NM_001405
RefSeq Peptide - NP_001396
swissprot - O43921
Ensembl - ENSG00000099617
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 efna2aENSDARG00000031372Danio rerio
 efna2bENSDARG00000079740Danio rerio
 EFNA2ENSGALG00000038629Gallus gallus
 Efna2ENSMUSG00000003070Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EFNA5 / P52803 / ephrin A5ENSG0000018434948
EFNA3 / P52797 / ephrin A3ENSG0000014359044
AL691442.1ENSG0000025124641
EFNA4 / P52798 / ephrin A4ENSG0000024336437
EFNA1 / P20827 / ephrin A1ENSG0000016924236


Protein motifs (from Interpro)
Interpro ID Name
 IPR001799  Ephrin receptor-binding domain
 IPR008972  Cupredoxin
 IPR019765  Ephrin, conserved site
 IPR031328  Ephrin
 IPR034252  Ephrin-A ectodomain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0021772 olfactory bulb development IEA
 biological_processGO:0030316 osteoclast differentiation IEA
 biological_processGO:0046849 bone remodeling IEA
 biological_processGO:0048013 ephrin receptor signaling pathway ISS
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0031594 neuromuscular junction IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046875 ephrin receptor binding TAS


Pathways (from Reactome)
Pathway description
EPH-Ephrin signaling
EPHA-mediated growth cone collapse
EPH-ephrin mediated repulsion of cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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