ENSG00000243364


Homo sapiens

Features
Gene ID: ENSG00000243364
  
Biological name :EFNA4
  
Synonyms : EFNA4 / ephrin A4 / P52798
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q21.3
Gene start: 155063731
Gene end: 155069553
  
Corresponding Affymetrix probe sets: 205107_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000352789
Ensembl peptide - ENSP00000357394
Ensembl peptide - ENSP00000414378
NCBI entrez gene - 1945     See in Manteia.
OMIM - 601380
RefSeq - NM_182689
RefSeq - NM_005227
RefSeq - NM_182690
RefSeq Peptide - NP_005218
RefSeq Peptide - NP_872631
RefSeq Peptide - NP_872632
swissprot - P52798
Ensembl - ENSG00000243364
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-246i14.3ENSDARG00000090427Danio rerio
 Efna4ENSMUSG00000028040Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AL691442.1ENSG0000025124643
EFNA3 / P52797 / ephrin A3ENSG0000014359039
EFNA2 / O43921 / ephrin A2ENSG0000009961738
EFNA5 / P52803 / ephrin A5ENSG0000018434934
EFNA1 / P20827 / ephrin A1ENSG0000016924232


Protein motifs (from Interpro)
Interpro ID Name
 IPR001799  Ephrin receptor-binding domain
 IPR008972  Cupredoxin
 IPR019765  Ephrin, conserved site
 IPR031328  Ephrin
 IPR034252  Ephrin-A ectodomain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007411 axon guidance IBA
 biological_processGO:0030316 osteoclast differentiation IBA
 biological_processGO:0046849 bone remodeling IBA
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0005005 transmembrane-ephrin receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046875 ephrin receptor binding IPI


Pathways (from Reactome)
Pathway description
EPH-Ephrin signaling
EPHA-mediated growth cone collapse
EPH-ephrin mediated repulsion of cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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