ENSG00000143590


Homo sapiens

Features
Gene ID: ENSG00000143590
  
Biological name :EFNA3
  
Synonyms : EFNA3 / ephrin A3 / P52797
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q21.3
Gene start: 155078872
Gene end: 155087538
  
Corresponding Affymetrix probe sets: 210132_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357393
NCBI entrez gene - 1944     See in Manteia.
OMIM - 601381
RefSeq - NM_004952
RefSeq Peptide - NP_004943
swissprot - P52797
Ensembl - ENSG00000143590
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 efna3aENSDARG00000014675Danio rerio
 efna3bENSDARG00000098295Danio rerio
 Efna3ENSMUSG00000028039Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AL691442.1ENSG0000025124689
EFNA2 / O43921 / ephrin A2ENSG0000009961739
EFNA5 / P52803 / ephrin A5ENSG0000018434935
EFNA4 / P52798 / ephrin A4ENSG0000024336434
EFNA1 / P20827 / ephrin A1ENSG0000016924234


Protein motifs (from Interpro)
Interpro ID Name
 IPR001799  Ephrin receptor-binding domain
 IPR008972  Cupredoxin
 IPR019765  Ephrin, conserved site
 IPR031328  Ephrin
 IPR034252  Ephrin-A ectodomain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007411 axon guidance IBA
 biological_processGO:0016525 negative regulation of angiogenesis IDA
 biological_processGO:0045664 regulation of neuron differentiation IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IGI
 biological_processGO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process IGI
 cellular_componentGO:0005886 plasma membrane NAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0005005 transmembrane-ephrin receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046875 ephrin receptor binding IPI


Pathways (from Reactome)
Pathway description
EPH-Ephrin signaling
EPHA-mediated growth cone collapse
EPH-ephrin mediated repulsion of cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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