ENSG00000100298


Homo sapiens

Features
Gene ID: ENSG00000100298
  
Biological name :APOBEC3H
  
Synonyms : APOBEC3H / apolipoprotein B mRNA editing enzyme catalytic subunit 3H / Q6NTF7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.1
Gene start: 39097224
Gene end: 39104067
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000393520
Ensembl peptide - ENSP00000385741
Ensembl peptide - ENSP00000411754
Ensembl peptide - ENSP00000483689
Ensembl peptide - ENSP00000482682
Ensembl peptide - ENSP00000216123
NCBI entrez gene - 164668     See in Manteia.
OMIM - 610976
RefSeq - XM_011529992
RefSeq - NM_001166002
RefSeq - NM_001166003
RefSeq - NM_001166004
RefSeq - NM_181773
RefSeq - XM_011529990
RefSeq - XM_011529991
RefSeq Peptide - NP_001159474
RefSeq Peptide - NP_001159476
RefSeq Peptide - NP_861438
RefSeq Peptide - NP_001159475
swissprot - A0A087WZI3
swissprot - Q6NTF7
swissprot - B7TQM4
swissprot - B7TQM3
swissprot - M4W6S4
Ensembl - ENSG00000100298
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q99J72ENSMUSG00000009585Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9HC16 / APOBEC3G / apolipoprotein B mRNA editing enzyme catalytic subunit 3GENSG0000023971333
Q9NRW3 / APOBEC3C / apolipoprotein B mRNA editing enzyme catalytic subunit 3CENSG0000024450933
Q8IUX4 / APOBEC3F / apolipoprotein B mRNA editing enzyme catalytic subunit 3FENSG0000012839432
AICDA / Q9GZX7 / activation induced cytidine deaminaseENSG0000011173232
AL022318.4ENSG0000028455431
Q96AK3 / APOBEC3D / apolipoprotein B mRNA editing enzyme catalytic subunit 3DENSG0000024381131
P31941 / APOBEC3A / apolipoprotein B mRNA editing enzyme catalytic subunit 3AENSG0000012838331
Q9UH17 / APOBEC3B / apolipoprotein B mRNA editing enzyme catalytic subunit 3BENSG0000017975030
Q9Y235 / APOBEC2 / apolipoprotein B mRNA editing enzyme catalytic subunit 2ENSG0000012470125
P41238 / APOBEC1 / apolipoprotein B mRNA editing enzyme catalytic subunit 1ENSG0000011170123


Protein motifs (from Interpro)
Interpro ID Name
 IPR002125  Cytidine and deoxycytidylate deaminase domain
 IPR013158  APOBEC-like, N-terminal
 IPR016192  APOBEC/CMP deaminase, zinc-binding
 IPR016193  Cytidine deaminase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0009972 cytidine deamination IEA
 biological_processGO:0010529 negative regulation of transposition IMP
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate IDA
 biological_processGO:0048525 negative regulation of viral process IMP
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0070383 DNA cytosine deamination IDA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004126 cytidine deaminase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
mRNA Editing: C to U Conversion
Formation of the Editosome


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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