ENSG00000124701


Homo sapiens

Features
Gene ID: ENSG00000124701
  
Biological name :APOBEC2
  
Synonyms : APOBEC2 / apolipoprotein B mRNA editing enzyme catalytic subunit 2 / Q9Y235
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.1
Gene start: 41053304
Gene end: 41064511
  
Corresponding Affymetrix probe sets: 206160_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000244669
NCBI entrez gene - 10930     See in Manteia.
OMIM - 604797
RefSeq - NM_006789
RefSeq Peptide - NP_006780
swissprot - Q9Y235
Ensembl - ENSG00000124701
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 apobec2aENSDARG00000018881Danio rerio
 apobec2bENSDARG00000113992Danio rerio
 APOBEC2ENSGALG00000003226Gallus gallus
 Q9WV35ENSMUSG00000040694Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UH17 / APOBEC3B / apolipoprotein B mRNA editing enzyme catalytic subunit 3BENSG0000017975030
Q9HC16 / APOBEC3G / apolipoprotein B mRNA editing enzyme catalytic subunit 3GENSG0000023971329
Q8IUX4 / APOBEC3F / apolipoprotein B mRNA editing enzyme catalytic subunit 3FENSG0000012839429
AL022318.4ENSG0000028455428
Q96AK3 / APOBEC3D / apolipoprotein B mRNA editing enzyme catalytic subunit 3DENSG0000024381128
AICDA / Q9GZX7 / activation induced cytidine deaminaseENSG0000011173227
Q9NRW3 / APOBEC3C / apolipoprotein B mRNA editing enzyme catalytic subunit 3CENSG0000024450925
P31941 / APOBEC3A / apolipoprotein B mRNA editing enzyme catalytic subunit 3AENSG0000012838325
Q6NTF7 / APOBEC3H / apolipoprotein B mRNA editing enzyme catalytic subunit 3HENSG0000010029822
P41238 / APOBEC1 / apolipoprotein B mRNA editing enzyme catalytic subunit 1ENSG0000011170119


Protein motifs (from Interpro)
Interpro ID Name
 IPR002125  Cytidine and deoxycytidylate deaminase domain
 IPR013158  APOBEC-like, N-terminal
 IPR016193  Cytidine deaminase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0009972 cytidine deamination IEA
 biological_processGO:0016554 cytidine to uridine editing IDA
 biological_processGO:0016556 mRNA modification IEA
 biological_processGO:0080111 DNA demethylation IDA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004126 cytidine deaminase activity IDA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
mRNA Editing: C to U Conversion
Formation of the Editosome


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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