ENSG00000100852


Homo sapiens

Features
Gene ID: ENSG00000100852
  
Biological name :ARHGAP5
  
Synonyms : ARHGAP5 / Q13017 / Rho GTPase activating protein 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q12
Gene start: 32076114
Gene end: 32159728
  
Corresponding Affymetrix probe sets: 1552627_a_at (Human Genome U133 Plus 2.0 Array)   217936_at (Human Genome U133 Plus 2.0 Array)   233849_s_at (Human Genome U133 Plus 2.0 Array)   233872_x_at (Human Genome U133 Plus 2.0 Array)   235635_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000452372
Ensembl peptide - ENSP00000452222
Ensembl peptide - ENSP00000452606
Ensembl peptide - ENSP00000371897
Ensembl peptide - ENSP00000379827
Ensembl peptide - ENSP00000393307
Ensembl peptide - ENSP00000407395
Ensembl peptide - ENSP00000441692
Ensembl peptide - ENSP00000451061
Ensembl peptide - ENSP00000451579
NCBI entrez gene - 394     See in Manteia.
OMIM - 602680
RefSeq - XM_017021288
RefSeq - NM_001030055
RefSeq - NM_001173
RefSeq - XM_005267635
RefSeq - XM_005267636
RefSeq - XM_017021287
RefSeq Peptide - NP_001164
RefSeq Peptide - NP_001025226
swissprot - G3V444
swissprot - G3V5I7
swissprot - H0YK04
swissprot - A0A0A0MSK6
swissprot - Q13017
swissprot - G3V360
Ensembl - ENSG00000100852
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap5ENSDARG00000061294Danio rerio
 ARHGAP5ENSGALG00000009992Gallus gallus
 Arhgap5ENSMUSG00000035133Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NRY4 / ARHGAP35 / Rho GTPase activating protein 35ENSG0000016000751
ARAP2 / Q8WZ64 / ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2ENSG0000004736512
ARAP3 / Q8WWN8 / ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3ENSG0000012031812
ARAP1 / Q96P48 / ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1ENSG0000018663511


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001806  Small GTPase superfamily
 IPR002713  FF domain
 IPR008936  Rho GTPase activation protein
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR032835  Rho GTPase-activating protein, FF domain
 IPR036517  FF domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007266 Rho protein signal transduction TAS
 biological_processGO:0030879 mammary gland development IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0042169 SH2 domain binding IPI


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr