ENSG00000101446


Homo sapiens

Features
Gene ID: ENSG00000101446
  
Biological name :SPINT3
  
Synonyms : P49223 / serine peptidase inhibitor, Kunitz type 3 / SPINT3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.12
Gene start: 45512461
Gene end: 45515624
  
Corresponding Affymetrix probe sets: 215503_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000217428
NCBI entrez gene - 10816     See in Manteia.
OMIM - 613941
RefSeq - NM_006652
RefSeq Peptide - NP_006643
swissprot - P49223
Ensembl - ENSG00000101446
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Spint3ENSMUSG00000074596Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TFPI / P10646 / tissue factor pathway inhibitorENSG0000000343637
O43291 / SPINT2 / serine peptidase inhibitor, Kunitz type 2ENSG0000016764234
AMBP / P02760 / alpha-1-microglobulin/bikunin precursorENSG0000010692729
O43278 / SPINT1 / serine peptidase inhibitor, Kunitz type 1ENSG0000016614527
TFPI2 / P48307 / tissue factor pathway inhibitor 2ENSG0000010582526
AC011479.1ENSG0000026774822
Q8TEU8 / WFIKKN2 / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2ENSG0000017371420
Q96NZ8 / WFIKKN1 / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1ENSG0000012757818


Protein motifs (from Interpro)
Interpro ID Name
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site
 IPR036880  Pancreatic trypsin inhibitor Kunitz domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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