ENSG00000105825


Homo sapiens

Features
Gene ID: ENSG00000105825
  
Biological name :TFPI2
  
Synonyms : P48307 / TFPI2 / tissue factor pathway inhibitor 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q21.3
Gene start: 93885397
Gene end: 93890991
  
Corresponding Affymetrix probe sets: 209277_at (Human Genome U133 Plus 2.0 Array)   209278_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000222543
Ensembl peptide - ENSP00000416370
NCBI entrez gene - 7980     See in Manteia.
OMIM - 600033
RefSeq - NM_001271004
RefSeq - NM_001271003
RefSeq - NM_006528
RefSeq Peptide - NP_001257932
RefSeq Peptide - NP_001257933
RefSeq Peptide - NP_006519
swissprot - P48307
swissprot - H7C4A3
Ensembl - ENSG00000105825
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tfpi2ENSDARG00000061351Danio rerio
 TFPI2ENSGALG00000009512Gallus gallus
 Tfpi2ENSMUSG00000029664Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TFPI / P10646 / tissue factor pathway inhibitorENSG0000000343634
O43278 / SPINT1 / serine peptidase inhibitor, Kunitz type 1ENSG0000016614526
O43291 / SPINT2 / serine peptidase inhibitor, Kunitz type 2ENSG0000016764223
Q8TEU8 / WFIKKN2 / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2ENSG0000017371422
Q96NZ8 / WFIKKN1 / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1ENSG0000012757822
AMBP / P02760 / alpha-1-microglobulin/bikunin precursorENSG0000010692719
AC011479.1ENSG0000026774817
P49223 / SPINT3 / serine peptidase inhibitor, Kunitz type 3ENSG0000010144610


Protein motifs (from Interpro)
Interpro ID Name
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR008296  Tissue factor pathway inhibitor-like
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site
 IPR036880  Pancreatic trypsin inhibitor Kunitz domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0007599 hemostasis IEA
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0071498 cellular response to fluid shear stress IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0005201 extracellular matrix structural constituent TAS
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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