ENSMUSG00000029664


Mus musculus

Features
Gene ID: ENSMUSG00000029664
  
Biological name :Tfpi2
  
Synonyms : O35536 / Tfpi2 / tissue factor pathway inhibitor 2
  
Possible biological names infered from orthology : P48307
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: A1
Gene start: 3962595
Gene end: 3988919
  
Corresponding Affymetrix probe sets: 10542953 (MoGene1.0st)   1418547_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031674
Ensembl peptide - ENSMUSP00000139066
Ensembl peptide - ENSMUSP00000145193
NCBI entrez gene - 21789     See in Manteia.
MGI - MGI:108543
RefSeq - XM_011241056
RefSeq - NM_009364
RefSeq - XM_006505043
RefSeq - XM_006505044
RefSeq - XM_011241055
RefSeq Peptide - NP_033390
swissprot - V9GXA8
swissprot - A0A0N4SVP7
swissprot - O35536
swissprot - Q3V1S9
Ensembl - ENSMUSG00000029664
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tfpi2ENSDARG00000061351Danio rerio
 TFPI2ENSGALG00000009512Gallus gallus
 TFPI2ENSG00000105825Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tfpi / O54819 / tissue factor pathway inhibitor / P10646*ENSMUSG0000002708231
Q9R097 / Spint1 / Kunitz-type protease inhibitor 1 / O43278* / serine peptidase inhibitor, Kunitz type 1*ENSMUSG0000002731525
Q9WU03 / Spint2 / Kunitz-type protease inhibitor 2 / O43291* / serine peptidase inhibitor, Kunitz type 2*ENSMUSG0000007422722
Ambp / Q07456 / Protein AMBP Alpha-1-microglobulin Inter-alpha-trypsin inhibitor light chain Trypstatin / P02760* / alpha-1-microglobulin/bikunin precursor*ENSMUSG0000002835621
Q7TQN3 / Wfikkn2 / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 / Q8TEU8*ENSMUSG0000004417720
Q8R0S6 / Wfikkn1 / WAP, FS, Ig, KU, and NTR-containing protein 1 / Q96NZ8* / WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1*ENSMUSG0000007119217
Spint3 / serine peptidase inhibitor, Kunitz type, 3 / P49223*ENSMUSG0000007459612


Protein motifs (from Interpro)
Interpro ID Name
 IPR002223  Pancreatic trypsin inhibitor Kunitz domain
 IPR008296  Tissue factor pathway inhibitor-like
 IPR020901  Proteinase inhibitor I2, Kunitz, conserved site
 IPR036880  Pancreatic trypsin inhibitor Kunitz domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0007599 hemostasis IEA
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0071498 cellular response to fluid shear stress IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0031012 extracellular matrix ISO
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr