ENSG00000101844


Homo sapiens

Features
Gene ID: ENSG00000101844
  
Biological name :ATG4A
  
Synonyms : ATG4A / autophagy related 4A cysteine peptidase / Q8WYN0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q22.3
Gene start: 108091668
Gene end: 108154671
  
Corresponding Affymetrix probe sets: 213115_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378354
Ensembl peptide - ENSP00000361320
Ensembl peptide - ENSP00000416218
Ensembl peptide - ENSP00000298131
Ensembl peptide - ENSP00000341833
Ensembl peptide - ENSP00000361306
NCBI entrez gene - 115201     See in Manteia.
OMIM - 300663
RefSeq - XM_011530842
RefSeq - NM_001321287
RefSeq - NM_001321288
RefSeq - NM_001321289
RefSeq - NM_001321290
RefSeq - NM_052936
RefSeq - NM_178270
RefSeq - NM_178271
RefSeq - XM_011530841
RefSeq Peptide - NP_001308218
RefSeq Peptide - NP_001308219
RefSeq Peptide - NP_443168
RefSeq Peptide - NP_840054
RefSeq Peptide - NP_840055
RefSeq Peptide - NP_001308217
RefSeq Peptide - NP_001308216
swissprot - H7BYM2
swissprot - A0A0A0MT61
swissprot - F8W7J2
swissprot - G5E979
swissprot - Q8WYN0
Ensembl - ENSG00000101844
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atg4aENSDARG00000014531Danio rerio
 ATG4AENSGALG00000008282Gallus gallus
 Atg4aENSMUSG00000079418Mus musculus
 Atg4a-psENSMUSG00000087119Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATG4B / Q9Y4P1 / autophagy related 4B cysteine peptidaseENSG0000016839754
ATG4D / Q86TL0 / autophagy related 4D cysteine peptidaseENSG0000013073430
ATG4C / Q96DT6 / autophagy related 4C cysteine peptidaseENSG0000012570329


Protein motifs (from Interpro)
Interpro ID Name
 IPR005078  Peptidase C54
 IPR033474  Autophagin-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IBA
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0006501 C-terminal protein lipidation IBA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006612 protein targeting to membrane IBA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0044804 autophagy of nucleus IBA
 biological_processGO:0051697 protein delipidation IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Macroautophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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