ENSG00000130734


Homo sapiens

Features
Gene ID: ENSG00000130734
  
Biological name :ATG4D
  
Synonyms : ATG4D / autophagy related 4D cysteine peptidase / Q86TL0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.2
Gene start: 10543895
Gene end: 10553418
  
Corresponding Affymetrix probe sets: 226871_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468780
Ensembl peptide - ENSP00000467906
Ensembl peptide - ENSP00000468290
Ensembl peptide - ENSP00000311318
Ensembl peptide - ENSP00000465089
Ensembl peptide - ENSP00000465716
Ensembl peptide - ENSP00000466439
Ensembl peptide - ENSP00000466759
Ensembl peptide - ENSP00000467223
Ensembl peptide - ENSP00000467407
Ensembl peptide - ENSP00000467694
NCBI entrez gene - 84971     See in Manteia.
OMIM - 611340
RefSeq - XM_006722927
RefSeq - NM_001281504
RefSeq - NM_032885
RefSeq Peptide - NP_001268433
RefSeq Peptide - NP_116274
swissprot - K7EPJ0
swissprot - K7EQ67
swissprot - K7EQN3
swissprot - K7ERK1
swissprot - K7ESM7
swissprot - Q86TL0
swissprot - K7EJA5
swissprot - K7EKP6
swissprot - K7EN30
swissprot - K7EMB9
swissprot - K7EP43
Ensembl - ENSG00000130734
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atg4daENSDARG00000043548Danio rerio
 atg4dbENSDARG00000088145Danio rerio
 Atg4dENSMUSG00000002820Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATG4C / Q96DT6 / autophagy related 4C cysteine peptidaseENSG0000012570344
ATG4A / Q8WYN0 / autophagy related 4A cysteine peptidaseENSG0000010184426
ATG4B / Q9Y4P1 / autophagy related 4B cysteine peptidaseENSG0000016839726


Protein motifs (from Interpro)
Interpro ID Name
 IPR005078  Peptidase C54


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IBA
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0006501 C-terminal protein lipidation IBA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006612 protein targeting to membrane IBA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0044804 autophagy of nucleus IBA
 biological_processGO:0051697 protein delipidation IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Macroautophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr